Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.41 |
| ▸ | TEK | Q02763 | 3/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30987390 | 0.86 | MIF (0.55) | CA2CA1CA5ACA5BNOTUM | |
| SCHEMBL30987381 | 0.86 | BCHE (0.62) | CA2CA1CA5ACA5BNOTUM | |
| SCHEMBL31158277 | 0.85 | FLT3 (0.58) | CA2CA1CA5ACA5BCA12 | |
| SCHEMBL30987379 | 0.84 | NOTUM (0.50) | CA2CA1NOTUMCA12CA9 | |
| SCHEMBL30987400 | 0.83 | STIM1 (0.52) | CA2CA1NOTUMCA12CA9 | |
| SCHEMBL28661942 | 0.82 | CA2 (0.49) | CA2CA1CA5ACA5BNOTUM | |
| SCHEMBL15040972 | 0.79 | CA2 (0.67) | CA2CA1CA5ACA5BCA12 | |
| SCHEMBL25055359 | 0.78 | MIF (0.74) | CA2CA1NOTUMCA12CA9 | |
| SCHEMBL30987380 | 0.78 | NOTUM (0.52) | CA2CA1CA5ACA5BNOTUM | |
| SCHEMBL30987377 | 0.78 | MIF (0.55) | CA2CA1CA5ACA5BNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133292-A1 | NOVEL CCR8 ANTAGONISTS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-06-27 | — | — | WO | claimed |
| WO-2024133292-A1 | NOVEL CCR8 ANTAGONISTS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-06-27 | — | — | WO | disclosed |