Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 2/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.44 |
| ▸ | FLT3 | P36888 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30987381 | 0.88 | BCHE (0.62) | MIFNOTUMCA1CA2CA12 | |
| SCHEMBL30987379 | 0.86 | NOTUM (0.50) | MIFNOTUMCA1CA2CA12 | |
| SCHEMBL25055359 | 0.86 | MIF (0.74) | MIFNOTUMCA1CA2CA12 | |
| SCHEMBL30987390 | 0.86 | MIF (0.55) | MIFNOTUMCA1CA2CA12 | |
| SCHEMBL30987393 | 0.82 | ABCG2 (0.57) | MIFNOTUMCA1CA2CA12 | |
| SCHEMBL18031115 | 0.79 | MAPK14 (0.60) | MIFCA1CA2CA12CA9 | |
| SCHEMBL3270459 | 0.79 | NOTUM (0.57) | MIFNOTUMCA1CA2CA12 | |
| SCHEMBL28927757 | 0.79 | BCHE (0.51) | MIFNOTUMCA1CA2CA12 | |
| SCHEMBL30987376 | 0.78 | CA2 (0.51) | MIFNOTUMCA1CA2CA12 | |
| SCHEMBL28068164 | 0.75 | PTGS2 (0.62) | CA1CA2CA12CA9PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133292-A1 | NOVEL CCR8 ANTAGONISTS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-06-27 | — | — | WO | claimed |
| WO-2024133292-A1 | NOVEL CCR8 ANTAGONISTS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-06-27 | — | — | WO | disclosed |