Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | LPL | P06858 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 3/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MC5R | P33032 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | ANPEP | P15144 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LAP3 | P28838 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL775018 | 0.80 | LPL (0.40) | LPLLIPGGAAANPEPALDH1A1 | |
| SCHEMBL775430 | 0.80 | KDM4E (0.36) | LPLLIPGMEN1ALDH1A1KMT2A | |
| SCHEMBL16176982 | 0.80 | LPL (0.36) | LPLLIPGL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL26621923 | 0.78 | LPL (0.41) | LPLLIPGGAAANPEPALDH1A1 | |
| SCHEMBL12822400 | 0.78 | MEN1 (0.41) | LPLLIPGGAAANPEPMEN1 | |
| SCHEMBL18662581 | 0.77 | LPL (0.40) | LPLLIPGGAAANPEPALDH1A1 | |
| SCHEMBL774936 | 0.77 | ALDH1A1 (0.41) | LPLLIPGMAPK1L3MBTL1GAA | |
| SCHEMBL17045815 | 0.76 | KMT2A (0.44) | L3MBTL1GAAMEN1ALDH1A1KMT2A | |
| SCHEMBL12822172 | 0.75 | GPR55 (0.42) | LPLLIPGANPEPLAP3 | |
| SCHEMBL774640 | 0.75 | LPL (0.38) | LPLLIPGGAAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2688896-A2 | PYRIDYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF | Exxonmobil Chemical Patents Inc. (US) | 2014-01-29 | — | — | EP | disclosed |
| WO-2012134613-A2 | PYRIDYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-10-04 | — | — | WO | disclosed |