Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL774936 | 0.83 | ALDH1A1 (0.41) | LPLLIPGGAAMEN1KMT2A | |
| SCHEMBL16176982 | 0.82 | LPL (0.36) | LPLLIPGCYP1A2MEN1KMT2A | |
| SCHEMBL12822400 | 0.77 | MEN1 (0.41) | LPLLIPGGAACYP1A2MEN1 | |
| SCHEMBL775430 | 0.77 | KDM4E (0.36) | LPLLIPGMEN1KMT2AKDM4E | |
| SCHEMBL26621923 | 0.76 | LPL (0.41) | LPLLIPGGAACYP1A2CYP2A6 | |
| SCHEMBL12822237 | 0.75 | NFKB1 (0.40) | LPLLIPGGAAMEN1KMT2A | |
| SCHEMBL775018 | 0.74 | LPL (0.40) | LPLLIPGGAACYP2A6KMT2A | |
| SCHEMBL18662581 | 0.74 | LPL (0.40) | LPLLIPGGAACYP2A6KMT2A | |
| SCHEMBL774348 | 0.74 | CYP1A2 (0.46) | LPLLIPGCYP1A2CYP2A6MEN1 | |
| SCHEMBL30149369 | 0.74 | CYP1A2 (0.46) | LPLLIPGCYP1A2CYP2A6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2989130-B1 | PYRIDYLDIAMIDE METAL CATALYSTS AND PROCESSES TO PRODUCE POLYOLEFINS | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2019-05-15 | — | — | EP | disclosed |
| US-9321858-B2 | Pyridyldiamide metal catalysts and processes to produce polyolefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2016-04-26 | — | — | US | disclosed |
| EP-2989130-A1 | PYRIDYLDIAMIDE METAL CATALYSTS AND PROCESSES TO PRODUCE POLYOLEFINS | ExxonMobil Chemical Patents Inc. (US) | 2016-03-02 | — | — | EP | disclosed |
| WO-2014176187-A1 | PYRIDYLDIAMIDE METAL CATALYSTS AND PROCESSES TO PRODUCE POLYOLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2014-10-30 | — | — | WO | disclosed |
| US-20140316089-A1 | Pyridyldiamide Metal Catalysts and Processes to Produce Polyolefins | EXXONMOBIL CHEMICAL PATENTS INC. | 2014-10-23 | — | — | US | disclosed |
| US-8710163-B2 | Pyridyldiamido transition metal complexes, production and use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2014-04-29 | — | — | US | disclosed |
| EP-2688896-A2 | PYRIDYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF | Exxonmobil Chemical Patents Inc. (US) | 2014-01-29 | — | — | EP | disclosed |
| US-8394902-B2 | Pyridyldiamido transition metal complexes, production and use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-03-12 | — | — | US | disclosed |
| WO-2012134613-A2 | PYRIDYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-10-04 | — | — | WO | disclosed |
| US-20120071616-A1 | Pyridyldiamido Transition Metal Complexes, Production And Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2012-03-22 | — | — | US | disclosed |
| US-20110301310-A1 | Pyridyldiamido Transition Metal Complexes, Production And Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301310-A1 | Pyridyldiamido Transition Metal Complexes, Production And Use Thereof | PNPO, PLPBP, PDXK | LPL 3171/4885LIPG 3759/4885GAA 2922/4885 |
| US-20120071616-A1 | Pyridyldiamido Transition Metal Complexes, Production And Use Thereof | PNPO, PLPBP, PDXK | LPL 3171/4885LIPG 3759/4885GAA 2922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.