SCHEMBL775018

SCHEMBL775018

CC1(C)OB(c2c(CBr)ccc3ccccc23)OC1(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPL P06858 2/20 0.40
LIPG Q9Y5X9 2/20 0.40
ANPEP P15144 1/20 0.33
LAP3 P28838 1/20 0.33
ALDH1A1 P00352 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
CYP2A6 P11509 1/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ROCK1 Q13464 1/20 0.32
HTR1A P08908 2/20 0.32
HTR7 P34969 2/20 0.32
HTR2B P41595 2/20 0.32
TMEM97 Q5BJF2 2/20 0.32
SIGMAR1 Q99720 2/20 0.32
KDM4E B2RXH2 2/20 0.32
MAPT P10636 2/20 0.32
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26621923 0.86 LPL (0.41) LPLLIPGANPEPLAP3ALDH1A1
SCHEMBL18662581 0.85 LPL (0.40) LPLLIPGANPEPLAP3ALDH1A1
SCHEMBL12822172 0.82 GPR55 (0.42) LPLLIPGANPEPLAP3
SCHEMBL12822237 0.80 NFKB1 (0.40) LPLLIPGANPEPLAP3ALDH1A1
SCHEMBL775430 0.79 KDM4E (0.36) LPLLIPGALDH1A1KDM4EKMT2A
SCHEMBL17065250 0.79 RAB9A (0.36) LPLLIPGALDH1A1HSD17B10
SCHEMBL16176982 0.79 LPL (0.36) LPLLIPGALDH1A1TDP1TSHR
SCHEMBL29024894 0.79 LIPG (0.39) LPLLIPGANPEPLAP3
SCHEMBL21446903 0.78 LPL (0.44) LPLLIPGANPEPLAP3ALDH1A1
SCHEMBL20829045 0.78 LPL (0.44) LPLLIPGANPEPLAP3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3286234-B1 MULTIMODAL AND BROAD MOLECULAR WEIGHT HIGH DENSITY POLYETHYLENE EXXONMOBIL CHEMICAL PATENTS INC (US) 2026-04-15 EP disclosed
EP-3286230-B1 SUPPORTED CATALYST SYSTEMS AND PROCESSES FOR USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-03-08 EP disclosed
CN-107636027-B Supported catalyst system and method of use 埃克森美孚化学专利公司 2023-01-03 CN disclosed
CN-108137730-B Polymerization process using pyridyldiamido compound supported on organoaluminum-treated layered silicate support 埃克森美孚化学专利公司 2021-10-29 CN disclosed
CN-109563110-B Quinolinyldiamido transition metal complexes, their production and use 埃克森美孚化学专利公司 2021-08-20 CN disclosed
EP-3478694-B9 QUINOLINYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC (US) 2021-08-04 EP disclosed
EP-3478694-B1 QUINOLINYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC (US) 2020-12-09 EP disclosed
CN-108137747-B Multimodal and broad molecular weight high density polyethylene 埃克森美孚化学专利公司 2020-10-27 CN disclosed
US-10815318-B2 Quinolinyldiamido transition metal complexes, production and use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-10-27 US disclosed
US-10676547-B2 Aluminum alkyls with pendant olefins on clays EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-06-09 US disclosed
EP-2688895-A1 PYRIDYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF Exxonmobil Chemical Patents Inc. (US) 2014-01-29 EP disclosed
EP-2688896-A2 PYRIDYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF Exxonmobil Chemical Patents Inc. (US) 2014-01-29 EP disclosed
EP-2688897-A1 PYRIDYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF Exxon-Mobil Chemical Patents Inc. (US) 2014-01-29 EP disclosed
US-8394902-B2 Pyridyldiamido transition metal complexes, production and use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-03-12 US disclosed
WO-2012134614-A1 PYRIDYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-10-04 WO disclosed
WO-2012134615-A1 PYRIDYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-10-04 WO disclosed
WO-2012134613-A2 PYRIDYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-10-04 WO disclosed
US-20120071616-A1 Pyridyldiamido Transition Metal Complexes, Production And Use Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2012-03-22 US disclosed
US-20110301310-A1 Pyridyldiamido Transition Metal Complexes, Production And Use Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2011-12-08 US disclosed
US-20110224391-A1 Pyridyldiamido Transition Metal Complexes, Production and Use Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2011-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110301310-A1 Pyridyldiamido Transition Metal Complexes, Production And Use Thereof PNPO, PLPBP, PDXK LPL 3171/4885LIPG 3759/4885ANPEP 1782/4885
US-20110224391-A1 Pyridyldiamido Transition Metal Complexes, Production and Use Thereof PICALM, PARN, PCBP1 LPL 3013/4885LIPG 3688/4885ANPEP 2509/4885
US-10815318-B2 Quinolinyldiamido transition metal complexes, production and use thereof PARN, PARG, PICALM LPL 4375/4885LIPG 4033/4885ANPEP 2478/4885
US-20120071616-A1 Pyridyldiamido Transition Metal Complexes, Production And Use Thereof PNPO, PLPBP, PDXK LPL 3171/4885LIPG 3759/4885ANPEP 1782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.