SCHEMBL774936

SCHEMBL774936

Cc1ccccc1NCc1ccc2ccccc2c1B1OC(C)(C)C(C)(C)O1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
HTT P42858 3/20 0.41
KMT2A Q03164 3/20 0.41
KDM4E B2RXH2 2/20 0.41
LMNA P02545 2/20 0.41
POLB P06746 1/20 0.41
ALOX12 P18054 1/20 0.41
MPI P34949 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MAPT P10636 4/20 0.41
MEN1 O00255 2/20 0.41
ADRA2C P18825 3/20 0.36
ADRA2B P18089 1/20 0.35
LPL P06858 1/20 0.34
LIPG Q9Y5X9 1/20 0.34
TP53 P04637 1/20 0.34
GAA P10253 1/20 0.34
MAPK1 P28482 1/20 0.34
HSD17B10 Q99714 1/20 0.34
NPC1 O15118 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16176982 0.84 LPL (0.36) ALDH1A1HTTKMT2AKDM4ELMNA
SCHEMBL774640 0.83 LPL (0.38) ALDH1A1KMT2AKDM4EMAPTMEN1
SCHEMBL16177172 0.83 MAPT (0.49) ALDH1A1HTTKMT2AKDM4ELMNA
SCHEMBL12822400 0.79 MEN1 (0.41) ALDH1A1KMT2AKDM4EMAPTMEN1
SCHEMBL775430 0.79 KDM4E (0.36) ALDH1A1HTTKMT2AKDM4EMEN1
SCHEMBL26621923 0.77 LPL (0.41) ALDH1A1HTTKMT2AKDM4ELMNA
SCHEMBL16177250 0.77 MAPT (0.50) ALDH1A1HTTKMT2AKDM4ELMNA
SCHEMBL12822172 0.77 GPR55 (0.42) LPLLIPG
SCHEMBL12822237 0.77 NFKB1 (0.40) ALDH1A1KMT2AKDM4EL3MBTL1MEN1
SCHEMBL18662581 0.76 LPL (0.40) ALDH1A1KMT2AKDM4ELMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3286234-B1 MULTIMODAL AND BROAD MOLECULAR WEIGHT HIGH DENSITY POLYETHYLENE EXXONMOBIL CHEMICAL PATENTS INC (US) 2026-04-15 EP disclosed
EP-3286230-B1 SUPPORTED CATALYST SYSTEMS AND PROCESSES FOR USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-03-08 EP disclosed
CN-107636027-B Supported catalyst system and method of use 埃克森美孚化学专利公司 2023-01-03 CN disclosed
US-11180580-B2 Benzazole and pseudoindole diamido transition metal complexes and use thereof in olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-11-23 US disclosed
EP-3478694-B9 QUINOLINYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC (US) 2021-08-04 EP disclosed
EP-3478694-B1 QUINOLINYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC (US) 2020-12-09 EP disclosed
US-10815318-B2 Quinolinyldiamido transition metal complexes, production and use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-10-27 US disclosed
CN-108137747-B Multimodal and broad molecular weight high density polyethylene 埃克森美孚化学专利公司 2020-10-27 CN disclosed
US-20200308315-A1 Benzazole and Pseudoindole Diamido Transition Metal Complexes and use Thereof in Olefin Polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2020-10-01 US disclosed
US-10647786-B2 Supported catalyst systems and processes for use thereof EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2020-05-12 US disclosed
EP-2953984-A1 PROCESS FOR CONTROLLING MOLECULAR WEIGHT OF POLYOLEFINS PREPARED USING PYRIDYL DIAMIDE CATALYST SYSTEMS ExxonMobil Chemical Patents Inc. (US) 2015-12-16 EP disclosed
US-9102773-B2 Process for controlling molecular weight of polyolefins prepared using pyridyl diamide catalyst systems EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-08-11 US disclosed
WO-2014176187-A1 PYRIDYLDIAMIDE METAL CATALYSTS AND PROCESSES TO PRODUCE POLYOLEFINS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-10-30 WO disclosed
US-20140316089-A1 Pyridyldiamide Metal Catalysts and Processes to Produce Polyolefins EXXONMOBIL CHEMICAL PATENTS INC. 2014-10-23 US disclosed
US-20140316089-A1 Pyridyldiamide Metal Catalysts and Processes to Produce Polyolefins EXXONMOBIL CHEMICAL PATENTS INC. 2014-10-23 US disclosed
US-20140316089-A1 Pyridyldiamide Metal Catalysts and Processes to Produce Polyolefins EXXONMOBIL CHEMICAL PATENTS INC. 2014-10-23 US disclosed
WO-2014123683-A1 PROCESS FOR CONTROLLING MOLECULAR WEIGHT OF POLYOLEFINS PREPARED USING PYRIDYL DIAMIDE CATALYST SYSTEMS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-08-14 WO disclosed
US-20140221587-A1 Process for Controlling Molecular Weight of Polyolefins Prepared Using Pyridyl Diamide Catalyst Systems EXXONMOBIL CHEMICAL PATENTS INC. 2014-08-07 US disclosed
US-8394902-B2 Pyridyldiamido transition metal complexes, production and use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-03-12 US disclosed
US-20120071616-A1 Pyridyldiamido Transition Metal Complexes, Production And Use Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10647786-B2 Supported catalyst systems and processes for use thereof PARG, PUF60, SCO2 ALDH1A1 3942/4885HTT 3464/4885KMT2A 2178/4885
US-10815318-B2 Quinolinyldiamido transition metal complexes, production and use thereof PARN, PARG, PICALM ALDH1A1 3944/4885HTT 1029/4885KMT2A 3052/4885
US-20120071616-A1 Pyridyldiamido Transition Metal Complexes, Production And Use Thereof PNPO, PLPBP, PDXK ALDH1A1 1554/4885HTT 4028/4885KMT2A 3516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.