Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2147182 | 0.76 | LMNA (0.37) | LMNA | |
| SCHEMBL15132948 | 0.69 | LMNA (0.32) | LMNA | |
| SCHEMBL8627227 | 0.63 | LMNA (0.40) | LMNA | |
| SCHEMBL16182104 | 0.60 | L3MBTL1 (0.41) | LMNA | |
| SCHEMBL22165408 | 0.58 | ATR (0.41) | LMNA | |
| SCHEMBL24867413 | 0.55 | KDM4E (0.50) | LMNA | |
| SCHEMBL19982883 | 0.55 | CRBN (0.33) | — | |
| SCHEMBL14026236 | 0.54 | MMP2 (0.46) | LMNA | |
| SCHEMBL2294837 | 0.54 | — | — | |
| SCHEMBL8629211 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011037795-A1 | COMPOUNDS WHICH SELECTIVELY MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-03-31 | — | — | WO | disclosed |