2'-Hydroxy-Flavanone

2'-Hydroxy-Flavanone

SCHEMBL128289

O=C1C[C@H](c2ccccc2O)Oc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
AR P10275 7/20 1.00
ADORA3 P0DMS8 3/20 1.00
HSD11B1 P28845 1/20 1.00
AKR1C3 P42330 1/20 1.00
CYP3A4 P08684 2/20 0.74
AXL P30530 1/20 0.72
NPC1 O15118 1/20 0.64
MAPT P10636 1/20 0.64
MAPK1 P28482 1/20 0.64
RAB9A P51151 1/20 0.64
MAOB P27338 3/20 0.64
KDM4E B2RXH2 1/20 0.64
CYP19A1 P11511 1/20 0.64
HSD17B10 Q99714 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2'-Hydroxy-Flavanone SCHEMBL128288 1.00 AR (1.00) ARADORA3HSD11B1AKR1C3CYP3A4
2'-Hydroxy-Flavanone SCHEMBL29661236 1.00 AR (1.00) ARADORA3HSD11B1AKR1C3CYP3A4
2'-Hydroxy-Flavanone SCHEMBL29661209 0.98 AR (0.97) ARADORA3HSD11B1AKR1C3CYP3A4
SCHEMBL9067953 0.90 AXL (0.84) ARADORA3HSD11B1AKR1C3CYP3A4
SCHEMBL9067956 0.90 AXL (0.84) ARADORA3HSD11B1AKR1C3CYP3A4
SCHEMBL5082108 0.85 AR (1.00) ARADORA3HSD11B1AKR1C3CYP3A4
SCHEMBL5082116 0.85 AR (0.80) ARADORA3HSD11B1AKR1C3CYP3A4
SCHEMBL28035030 0.85 AR (0.74) ARADORA3HSD11B1AKR1C3CYP3A4
SCHEMBL8093300 0.81 ADORA3 (0.68) ARADORA3HSD11B1AKR1C3CYP3A4
SCHEMBL1891296 0.81 AR (0.68) ARADORA3HSD11B1AKR1C3CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 371 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12571757-B2 Electrochemical pH sensor ANB SENSORS LTD (GB) 2026-03-10 US claimed
EP-4217721-B1 ELECTROCHEMICAL PH SENSOR ANB SENSORS LTD (GB) 2025-08-27 EP claimed
WO-2025091065-A1 FLAVONOID COMPOSITION GRETALS AUSTRALIA PTY LTD (AU) 2025-05-08 WO claimed
US-20230324325-A1 ELECTROCHEMICAL PH SENSOR ANB SENSORS LTD (GB) 2023-10-12 US claimed
EP-4217721-A1 ELECTROCHEMICAL PH SENSOR ANB Sensors Limited (GB) 2023-08-02 EP claimed
CN-116368382-A Electrochemical pH sensor ANB传感器有限公司 2023-06-30 CN claimed
US-20230172901-A1 COMPOSITIONS AND METHODS FOR THE PROPHYLAXIS AND TREATMENT OF FIBROTIC AND INFLAMMATORY CONDITIONS GRETALS AUSTRALIA PTY LTD (AU) 2023-06-08 US claimed
EP-4146194-A1 COMPOSITIONS AND METHODS FOR THE PROPHYLAXIS AND TREATMENT OF FIBROTIC AND INFLAMMATORY CONDITIONS Gretals Australia Pty Ltd (AU) 2023-03-15 EP claimed
WO-2022063936-A1 ELECTROCHEMICAL PH SENSOR ANB SENSORS LTD (GB) 2022-03-31 WO claimed
WO-2021222987-A1 COMPOSITIONS AND METHODS FOR THE PROPHYLAXIS AND TREATMENT OF FIBROTIC AND INFLAMMATORY CONDITIONS GRETALS AUSTRALIA PTY LTD (AU) 2021-11-11 WO claimed
US-20040086983-A1 Method for producing a heterocyclic compound and an aromatic carboxylic acid having one or more hydroxyl groups, and modified aromatic ring dioxygenase MARINE BIOTHECHNOLOGY INSTITUTE., LTD. (JP) 2004-05-06 US claimed
US-12571757-B2 Electrochemical pH sensor ANB SENSORS LTD (GB) 2026-03-10 US disclosed
US-20260033492-A1 Pest Repellents and Uses Thereof SENSORYGEN INC (US) 2026-02-05 US disclosed
EP-4217721-B1 ELECTROCHEMICAL PH SENSOR ANB SENSORS LTD (GB) 2025-08-27 EP disclosed
WO-2025091065-A1 FLAVONOID COMPOSITION GRETALS AUSTRALIA PTY LTD (AU) 2025-05-08 WO disclosed
US-6093411-A AN EMULSION COMPRISING FLAVONOIDS FOR PREVENTING OR TREATING SKIN DISORDERS THE PROCTER & GAMBLE COMPANY (US) 2000-07-25 US disclosed
US-6051602-A METHODS FOR PREVENTION OR TREATING SKIN DISORDERS USING FLAVONOID COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2000-04-18 US disclosed
WO-1999047118-A1 COMPOSITIONS FOR REGULATING SKIN APPEARANCE THE PROCTER & GAMBLE COMPANY (US) 1999-09-23 WO disclosed
WO-1999047113-A1 COMPOSITIONS FOR REGULATING SKIN APPEARANCE THE PROCTER & GAMBLE COMPANY (US) 1999-09-23 WO disclosed
WO-1999047119-A1 METHODS FOR REGULATING SKIN APPEARANCE THE PROCTER & GAMBLE COMPANY (US) 1999-09-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12571757-B2 Electrochemical pH sensor SCO2, ASIC1, NOX4 AR 4334/4885ADORA3 4781/4885HSD11B1 2887/4885
US-20260033492-A1 Pest Repellents and Uses Thereof F3, TFPI, FLI1 AR 4093/4885ADORA3 4878/4885HSD11B1 4755/4885
US-20230172901-A1 COMPOSITIONS AND METHODS FOR THE PROPHYLAXIS AND TREATMENT OF FIBROTIC AND INFLAMMATORY CONDITIONS MMP1, COL1A1, SERPINB1 AR 3364/4885ADORA3 3637/4885HSD11B1 1697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.