Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.37 |
| ▸ | RECQL | P46063 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | APEX1 | P27695 | 2/20 | 0.37 |
| ▸ | RAF1 | P04049 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12846567 | 0.79 | MAPT (0.41) | STAT3ALDH1A1KDM4EMEN1MAPT | |
| Dioncoquinone B SCHEMBL3401149 | 0.79 | MEN1 (0.60) | STAT3ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL12846651 | 0.75 | STAT3 (0.36) | STAT3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL5810491 | 0.72 | MEN1 (0.52) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL30004289 | 0.72 | MEN1 (0.52) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| Droserone SCHEMBL5858407 | 0.72 | MAOA (0.67) | STAT3ALDH1A1KDM4EMEN1MAPT | |
| Droserone SCHEMBL30003199 | 0.72 | MAOA (0.67) | STAT3ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL16528190 | 0.68 | GABRA1 (0.41) | ESR1ESR2TRPA1 | |
| SCHEMBL30026897 | 0.66 | TRPA1 (0.48) | ALDH1A1KDM4EHPGDHSD17B10TP53 | |
| SCHEMBL858277 | 0.66 | TRPA1 (0.48) | ALDH1A1KDM4EHPGDHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2093207-A1 | Antiinfective and antitumoral compounds isolated from tropical lianas | Julius-Maximilians-Universität Würzburg (DE) | 2009-08-26 | — | — | EP | disclosed |