Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12452054 | 0.98 | TSHR (0.42) | TSHRCYP3A4ALDH1A1CES2ZDHHC20 | |
| SCHEMBL22856582 | 0.98 | TSHR (0.42) | TSHRCYP3A4ALDH1A1CES2ZDHHC20 | |
| SCHEMBL23945567 | 0.87 | CES2 (0.44) | TSHRALDH1A1CES2ZDHHC20DNM1 | |
| SCHEMBL19631974 | 0.86 | NR1I2 (0.39) | TSHRALDH1A1DNM1 | |
| SCHEMBL22856483 | 0.85 | TSHR (0.41) | TSHRCYP3A4ALDH1A1CES2ZDHHC20 | |
| SCHEMBL22793905 | 0.82 | TSHR (0.45) | TSHRCYP3A4ALDH1A1CES2ZDHHC20 | |
| SCHEMBL24668885 | 0.82 | ALDH1A1 (0.44) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL16355252 | 0.82 | THRA (0.38) | TSHRCYP3A4ALDH1A1CES2ZDHHC20 | |
| SCHEMBL22849684 | 0.82 | KDM4C (0.34) | — | |
| SCHEMBL28047108 | 0.82 | EPHX2 (0.40) | TSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110065767-A1 | Substituted CC-1065 Analogs and Their Conjugates | SYNTARGA B.V. (NL) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065767-A1 | Substituted CC-1065 Analogs and Their Conjugates | PCNA, TOP1, TOP2B | TSHR 2338/4885CYP3A4 3691/4885ALDH1A1 2231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.