Sugi Predict

Sugi Predict / Compounds / SCHEMBL128520

SCHEMBL128520

SCHEMBL128520

N=Nc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PLAU P00749 1/20 0.55
▸ NOS1 P29475 4/20 0.53
▸ ALDH1A1 P00352 4/20 0.50
▸ HSD17B10 Q99714 2/20 0.50
▸ ACHE P22303 1/20 0.50
▸ LMNA P02545 1/20 0.48
▸ NOS3 P29474 2/20 0.47
▸ CES1 P23141 1/20 0.46
▸ MEN1 O00255 1/20 0.46
▸ MAPT P10636 1/20 0.46
▸ MAPK1 P28482 1/20 0.46
▸ CASP3 P42574 1/20 0.46
▸ RAB9A P51151 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ SENP8 Q96LD8 1/20 0.46
▸ SENP7 Q9BQF6 1/20 0.46
▸ SENP6 Q9GZR1 1/20 0.46
▸ CA1 P00915 2/20 0.45
▸ CA2 P00918 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3173958 0.80 PLAU (0.59) PLAUNOS1ALDH1A1HSD17B10ACHE
SCHEMBL3282776 0.80 MEN1 (0.61) PLAUNOS1ALDH1A1HSD17B10ACHE
SCHEMBL3282773 0.80 MEN1 (0.61) PLAUNOS1ALDH1A1HSD17B10ACHE
SCHEMBL22567 0.79 ALDH1A1 (0.72) ALDH1A1HSD17B10ACHELMNACES1
SCHEMBL27909482 0.79 ALDH1A1 (0.72) ALDH1A1HSD17B10ACHELMNACES1
SCHEMBL4365351 0.78 PLAU (0.57) PLAUNOS1ALDH1A1HSD17B10ACHE
SCHEMBL12155535 0.76 PLAU (0.55) PLAUNOS1ALDH1A1HSD17B10ACHE
SCHEMBL4168380 0.76 NOS1 (0.59) PLAUNOS1ALDH1A1HSD17B10ACHE
SCHEMBL128519 0.76 PLAU (0.55) PLAUNOS1ALDH1A1HSD17B10ACHE
Water SCHEMBL28241270 0.76 ALDH1A1 (0.68) ALDH1A1HSD17B10ACHELMNACES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 334 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220404323-A1 INDICATOR MATERIAL COMPRISING A POLYMERIC GEL CARRIER AND POLYMERIC INDICATOR MOOW.FARM KFT. (HU) 2022-12-22 — — US claimed
CN-110372534-A A kind of 4- nitrophenylazo vanillic aldehyde and its preparation method and application 莆田学院 2019-10-25 — — CN claimed
CN-109824607-A A kind of preparation method of bis-azo compound diazo component 上海应用技术大学 2019-05-31 — — CN claimed
CN-106459812-A Method for lubricating an internal combustion engine 路博润公司 2017-02-22 — — CN claimed
US-8476390-B2 Light filters comprising P-nitrophenylazo salicylic acid derivatives thereof ARES CAPITAL CORPORATION, AS COLLATERAL AGENT 2013-07-02 — — US claimed
US-8304537-B2 Use of oxazine compounds for making chromogenic materials THE UNIVERSITY OF MIAMI (US) 2012-11-06 — — US claimed
US-8119778-B2 Reversibly thermochromic compositions BASF SE (DE) 2012-02-21 — — US claimed
EP-2032370-B1 REVERSIBLY THERMOCHROMIC COMPOSITIONS BASF SE (DE) 2010-11-10 — — EP claimed
US-20100256306-A1 LIGHT FILTERS COMPRISING P-NITROPHENYLAZO SALICYLIC ACID DERIVATIVES THEREOF ARES CAPITAL CORPORATION, AS COLLATERAL AGENT 2010-10-07 — — US claimed
US-20100234494-A1 Reversibly thermochromic compositions CIBA CORPORATION 2010-09-16 — — US claimed
US-5011924-A Measurement Of Ions TECHNICON INSTRUMENTS CORPORATION (US) 1991-04-30 — — US claimed
US-4994395-A Determination of potassium cations TECHNICON INSTRUMENTS CORPORATION (US) 1991-02-19 — — US claimed
US-4992381-A Method of detecting electrolytes in an aqueous test sample using chromogenic hemispherands and test device therefor TECHNICON INSTRUMENTS CORPORATION (US) 1991-02-12 — — US claimed
US-4859606-A Method for detecting cations in a test sample utilizing chromogenic cryptahemispherands TECHNICON INSTRUMENTS CORPORATION (US) 1989-08-22 — — US claimed
US-4808539-A CRYPT COMPOUNDS TECHNICON INSTRUMENTS CORPORATION (US) 1989-02-28 — — US claimed
EP-0287330-A2 Chromogenic hemispherands useful for detecting electrolytes Bayer Corporation (US) 1988-10-19 — — EP claimed
EP-0287327-A2 Compounds for determining cations Bayer Corporation (US) 1988-10-19 — — EP claimed
EP-0287329-A2 Chromogenic cryptahemispherands useful in detecting electrolytes Bayer Corporation (US) 1988-10-19 — — EP claimed
US-4113720-A Disperse azo dye with diaminopyrimidine coupling component BASF AKTIENGESELLSCHAFT (DE) 1978-09-12 — — US claimed
US-4011208-A 3-CYANO OR ACYL-4-ARYL-5-ARYLAZO-6-HYDROXYPYRIDONE-2 DYES SANDOZ LTD. (CH) 1977-03-08 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100234494-A1 Reversibly thermochromic compositions CRY1, REL, CRY2 PLAU 4821/4885NOS1 194/4885ALDH1A1 3798/4885
US-20100256306-A1 LIGHT FILTERS COMPRISING P-NITROPHENYLAZO SALICYLIC ACID DERIVATIVES THEREOF UACA, SUN2, VHL PLAU 2187/4885NOS1 2239/4885ALDH1A1 356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.