SCHEMBL12856496

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13333766	0.90	CYP1A2 (0.42)	TDP1CYP2A6L3MBTL1HTTNPSR1
	SCHEMBL12856443	0.90	L3MBTL1 (0.44)	TDP1CYP2A6L3MBTL1HTTNPSR1
	SCHEMBL12856520	0.89	CYP1A2 (0.40)	TDP1CYP2A6L3MBTL1HTTNPSR1
	SCHEMBL15137921	0.88	ALDH1A1 (0.47)	TDP1CYP2A6L3MBTL1CYP3A4HSD17B10
	SCHEMBL10354363	0.87	ALDH1A1 (0.35)	TDP1CYP2A6L3MBTL1CYP3A4HSD17B10
	SCHEMBL10053535	0.87	L3MBTL1 (0.43)	TDP1CYP2A6L3MBTL1HTTNPSR1
	SCHEMBL13367581	0.87	ALDH1A1 (0.51)	TDP1CYP2A6L3MBTL1HTTNPSR1
	SCHEMBL12856498	0.86	ALDH1A1 (0.34)	TDP1CYP2A6L3MBTL1NPSR1CYP3A4
	SCHEMBL21979757	0.86	CYP1A2 (0.46)	TDP1CYP2A6L3MBTL1HTTNPSR1
	SCHEMBL12856564	0.85	ACHE (0.38)	TDP1CYP2A6L3MBTL1CYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.