SCHEMBL12856498

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10354363	0.92	ALDH1A1 (0.35)	ALDH1A1L3MBTL1CYP3A4TDP1HPGD
	SCHEMBL12576035	0.91	ALDH1A1 (0.31)	ALDH1A1L3MBTL1CYP3A4TDP1HPGD
	SCHEMBL12856564	0.89	ACHE (0.38)	ALDH1A1L3MBTL1CYP3A4TDP1HPGD
	SCHEMBL25069433	0.89	SIGMAR1 (0.38)	ALDH1A1L3MBTL1CYP3A4TDP1HPGD
	SCHEMBL1702512	0.89	SIGMAR1 (0.38)	ALDH1A1L3MBTL1CYP3A4TDP1HPGD
	SCHEMBL15137921	0.89	ALDH1A1 (0.47)	ALDH1A1L3MBTL1CYP3A4TDP1HPGD
	SCHEMBL12575565	0.88	ALDH1A1 (0.31)	ALDH1A1L3MBTL1CYP3A4TDP1HPGD
	SCHEMBL14184517	0.87	—	—
	SCHEMBL1753824	0.87	CYP2C19 (0.37)	ALDH1A1L3MBTL1CYP3A4TDP1HPGD
	SCHEMBL22746698	0.87	CYP2C19 (0.37)	ALDH1A1L3MBTL1CYP3A4TDP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.