Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.39 |
| ▸ | PTPRB | P23467 | 5/20 | 0.39 |
| ▸ | PTPRC | P08575 | 4/20 | 0.39 |
| ▸ | GSTA1 | P08263 | 4/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 4/20 | 0.39 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SELL | P14151 | 1/20 | 0.39 |
| ▸ | SELP | P16109 | 1/20 | 0.39 |
| ▸ | SELE | P16581 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPN | P05981 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18538300 | 1.00 | ACHE (0.39) | ACHEPTPN2PTPN1PTPN11PTPRB | |
| SCHEMBL13287042 | 0.88 | SELL (0.48) | ACHEPTPN2PTPN1PTPN11PTPRB | |
| SCHEMBL12856781 | 0.85 | GSTA1 (0.41) | ACHEPTPN2PTPN1PTPN11PTPRB | |
| SCHEMBL19762894 | 0.84 | ING2 (0.68) | PTPN2PTPN1PTPN11PTPRBPTPRC | |
| SCHEMBL18538310 | 0.83 | PTPN1 (0.43) | PTPN2PTPN1PTPN11PTPRBALDH1A1 | |
| SCHEMBL29644944 | 0.83 | ALDH1A1 (0.48) | PTPN2PTPN1PTPN11PTPRBPTPRC | |
| SCHEMBL29366399 | 0.83 | ALDH1A1 (0.48) | PTPN2PTPN1PTPN11PTPRBPTPRC | |
| SCHEMBL29383145 | 0.83 | ALDH1A1 (0.48) | PTPN2PTPN1PTPN11PTPRBPTPRC | |
| SCHEMBL2471777 | 0.83 | ALDH1A1 (0.48) | PTPN2PTPN1PTPN11PTPRBPTPRC | |
| SCHEMBL29469562 | 0.83 | ALDH1A1 (0.48) | PTPN2PTPN1PTPN11PTPRBPTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028676-A1 | Molecular Actuators, and Methods of Use Thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-02-03 | — | — | US | disclosed |
| US-7658868-B2 | Class of molecular actuators where bulk actuation mechanisms such as ion intercalation are enhanced by controllable single molecule conformational rearrangements offers promise in exhibiting large active strains at moderate stresses | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-02-09 | — | — | US | disclosed |
| US-20070215839-A1 | Molecular actuators, and methods of use thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070215839-A1 | Molecular actuators, and methods of use thereof | NOD2, PIEZO1, TPR | ACHE 3471/4885PTPN2 3195/4885PTPN1 3727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.