Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12859318 | 0.88 | CNR1 (0.40) | L3MBTL1ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL12859345 | 0.87 | KIF11 (0.39) | ALDH1A1KDM4ETDP1HPGDPOLB | |
| SCHEMBL12859307 | 0.85 | RECQL (0.40) | ALDH1A1KDM4EMAPTTDP1HPGD | |
| SCHEMBL12859323 | 0.83 | LMNA (0.38) | L3MBTL1ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL12859333 | 0.83 | TDP2 (0.39) | TDP2GRM5HTR2AHTR2CHTR2B | |
| SCHEMBL12859325 | 0.83 | ATM (0.40) | L3MBTL1ALDH1A1KDM4EPTGS2MAPT | |
| SCHEMBL23401734 | 0.80 | GRM5 (0.36) | ALDH1A1KDM4EPTGS2MAPTLMNA | |
| SCHEMBL14996540 | 0.79 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1KDM4EPTGS2MAPT | |
| SCHEMBL12859317 | 0.77 | PDE2A (0.42) | L3MBTL1ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL12856369 | 0.73 | NPC1 (0.40) | ALDH1A1KDM4EMAPTGRM5TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8455398-B2 | Amide compounds, preparation methods and uses thereof | SINOCHEM CORPORATION (CN) | 2013-06-04 | — | — | US | disclosed |
| US-20110046152-A1 | Amide Compounds, Preparation Methods and Uses Thereof | SINOCHEM CORPORATION | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046152-A1 | Amide Compounds, Preparation Methods and Uses Thereof | ACHE, MGAM, PGLS | L3MBTL1 131/4885ALDH1A1 1163/4885KDM4E 371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.