SCHEMBL128622

SCHEMBL128622

CC(C)c1ccc(COc2ccccc2C(=O)O)cc1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RXRA P19793 4/20 0.57
RXRB P28702 3/20 0.57
KDM4E B2RXH2 1/20 0.53
FOLH1 Q04609 1/20 0.52
PTGER1 P34995 1/20 0.52
ALDH1A1 P00352 2/20 0.51
RXRG P48443 1/20 0.51
HPGD P15428 1/20 0.51
PARP1 P09874 1/20 0.51
SGMS2 Q8NHU3 2/20 0.50
HPD P32754 1/20 0.50
KMT2A Q03164 1/20 0.50
PTK2B Q14289 1/20 0.50
MRGPRX4 Q96LA9 1/20 0.49
APEX1 P27695 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7908648 0.85 RXRA (0.61) RXRARXRBKDM4EFOLH1MRGPRX4
Salicylic Acid SCHEMBL29663592 0.85 RAB9A (0.46) RXRARXRBKDM4EFOLH1PTGER1
Salicylic Acid SCHEMBL6247293 0.85 RAB9A (0.46) RXRARXRBKDM4EFOLH1PTGER1
SCHEMBL112903 0.84 SGMS2 (0.66) KDM4EFOLH1PTGER1ALDH1A1PARP1
SCHEMBL29433417 0.84 SGMS2 (0.66) KDM4EFOLH1PTGER1ALDH1A1PARP1
SCHEMBL6391576 0.84 MCL1 (0.56) RXRARXRBKDM4EFOLH1PTGER1
SCHEMBL382849 0.84 FOLH1 (0.62) RXRARXRBKDM4EFOLH1PTGER1
SCHEMBL1388182 0.83 PTGER1 (0.60) RXRARXRBKDM4EFOLH1PTGER1
SCHEMBL2452396 0.83 FOLH1 (0.56) RXRARXRBKDM4EFOLH1PTGER1
SCHEMBL5839101 0.83 ALDH1A1 (0.59) RXRARXRBKDM4EFOLH1PTGER1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 578 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2545896-B1 Sunscreen compositions HENKEL AG & CO KGAA (DE) 2019-10-16 EP claimed
EP-2485807-B1 SUN-CARE COMPOSITIONS ISP INVESTMENTS LLC (US) 2019-07-03 EP claimed
EP-2545900-B1 Sun screen compounds with high sun block factor and pleasant feel HENKEL AG & CO KGAA (DE) 2018-08-08 EP claimed
EP-2545901-B1 Emulsion base for sun screen compounds HENKEL AG & CO KGAA (DE) 2017-11-22 EP claimed
EP-2384738-B1 Use of salicylic acid esters for masking the odour of degradation products from urea BEIERSDORF AG (DE) 2017-11-01 EP claimed
EP-2800741-B1 DUALISTIC MOLECULES HAVING UV RADIATION FILTRATING ABILITY AT WIDE SPECTRUM AND POTENT DAMPING ACTIVITY OF THE REACTIVITY OF FREE RADICALS (RADICALS SCAVENGING) Università degli Studi di Ferrara (IT) 2017-03-15 EP claimed
EP-2379625-B1 UV AND LIGHT PROTECTIVE FILM HUHTAMAKI FORCHHEIM (DE) 2013-02-20 EP claimed
EP-2545896-A2 Sunscreen compositions Henkel AG & Co. KGaA (DE) 2013-01-16 EP claimed
EP-2545900-A2 Sun screen compounds with high sun block factor and pleasant feel Henkel AG & Co. KGaA (DE) 2013-01-16 EP claimed
EP-2545901-A2 Emulsion base for sun screen compounds Henkel AG & Co. KGaA (DE) 2013-01-16 EP claimed
EP-0803244-A2 Cosmetic and dermatological photoprotective comportions containing a triazine derivative and mono- and diesters of branched alkanecarboxylic acids and diglycerin or triglycerin Beiersdorf Aktiengesellschaft (DE) 1997-10-29 EP claimed
EP-0801944-A2 Cosmetic and dermatological photoprotective compositions containing a triazine derivative and glycerin esters of alpha-hydroxycarboxylic acids and saturated fatty acids Beiersdorf Aktiengesellschaft (DE) 1997-10-22 EP claimed
EP-0800816-A2 Cosmetic and dermatological photoprotective compositions containing a triazine derivative and dialkyl esters of alpha, beta-hydroxycarboxylic acids Beiersdorf Aktiengesellschaft (DE) 1997-10-15 EP claimed
EP-0800817-A2 Cosmetic and dermatological photoprotective compositions containing a triazine derivative and monoalkyl esters of aplha-hydroxycarboxylic acids Beiersdorf Aktiengesellschaft (DE) 1997-10-15 EP claimed
EP-0800818-A2 Cosmetic and dermatological photoprotective compositions containing a triazine derivative and esters of propyleneglycol Beiersdorf Aktiengesellschaft (DE) 1997-10-15 EP claimed
EP-0787483-A1 Photostable, emulsifier-free cosmetic compositions Sara Lee/DE N.V. (NL) 1997-08-06 EP claimed
EP-0786246-A1 Cosmetic and dermatological sunscreen formulations containing triazine derivatives and glycerylcompounds Beiersdorf Aktiengesellschaft (DE) 1997-07-30 EP claimed
EP-0596424-B1 Process of 4-isopropylbenzylsalicilate as cutaneous anti-lipoperoxidant RIALDI GIORGIO (IT) 1997-01-08 EP claimed
US-5443818-A Cosmetic-dermatological sunscreen agent RIALDI GIORGIO (IT) 1995-08-22 US claimed
EP-0596424-A1 Process of 4-isopropylbenzylsalicilate as cutaneous anti-lipoperoxidant Rialdi, Giorgio (IT) 1994-05-11 EP claimed