SCHEMBL1286576

SCHEMBL1286576

O=C(NC(=O)C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.38
THRB P10828 1/20 0.33
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1618655 0.91 CA2 (0.46) CA2ALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL17577419 0.81 THRB (0.42) CA2THRBALDH1A1MEN1KMT2A
SCHEMBL27527472 0.79 ALDH1A1 (0.30) ALDH1A1POLBSMN1; SMN2
SCHEMBL9420216 0.75 DGAT1 (0.36) CA2THRBALDH1A1
SCHEMBL15598617 0.75 CA2 (0.35) CA2THRB
SCHEMBL2053132 0.72 CA2 (0.59) CA2ALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL47344 0.69 ALDH1A1 (0.36) CA2ALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL155467 0.69 MLYCD (0.42) CA2ALDH1A1MEN1KMT2A
SCHEMBL17577421 0.68 ALDH1A1 (0.37) CA2THRBALDH1A1
SCHEMBL19170051 0.68 EGLN1 (0.37) THRBALDH1A1POLBSMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120086892-A1 ADHESIVE COMPOSITION LG CHEM, LTD. (KR) 2012-04-12 US claimed
US-20100188620-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVE COMPOSITIONS LG CHEM, LTD. (KR) 2010-07-29 US claimed
US-9499725-B2 Acrylic pressure-sensitive adhesive compositions LG CHEM, LTD. (KR) 2016-11-22 US disclosed
US-20100188620-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVE COMPOSITIONS LG CHEM, LTD. (KR) 2010-07-29 US disclosed
EP-2147072-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVE COMPOSITIONS LG Chem, Ltd. (KR) 2010-01-27 EP disclosed
WO-2008130136-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVE COMPOSITIONS LG CHEM, LTD. (KR) 2008-10-30 WO disclosed