Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PTGES | O14684 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18078982 | 0.77 | — | — | |
| SCHEMBL8083467 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4EPOLBMAOA | |
| SCHEMBL13191817 | 0.75 | ALDH1A1 (0.45) | ALDH1A1MAPTKDM4EPOLBMAOA | |
| SCHEMBL19130728 | 0.74 | POLB (0.41) | ALDH1A1MAPTKDM4EPTGESALOX5 | |
| SCHEMBL4067426 | 0.74 | ALDH1A1 (0.40) | ALDH1A1MAPTKDM4EPTGESALOX5 | |
| SCHEMBL23364439 | 0.74 | ALDH1A1 (0.37) | ALDH1A1MAPTKDM4EPTGESALOX5 | |
| SCHEMBL7323969 | 0.73 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4EPOLBMAOA | |
| SCHEMBL7323961 | 0.73 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4EPTGESALOX5 | |
| SCHEMBL12018164 | 0.71 | POLB (0.41) | ALDH1A1MAPTKDM4EPTGESALOX5 | |
| SCHEMBL21786201 | 0.70 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4EPOLBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028337-A1 | NUCLEOBASE CHARACTERISATION | NUCLEOBASE CHARACTERISATION | 2011-02-03 | — | — | US | disclosed |
| US-20110028337-A1 | NUCLEOBASE CHARACTERISATION | NUCLEOBASE CHARACTERISATION | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028337-A1 | NUCLEOBASE CHARACTERISATION | NT5C3B, NT5C2, NT5E | ALDH1A1 1539/4885MAPT 3324/4885KDM4E 3588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.