SCHEMBL1289385

SCHEMBL1289385

Cc1cccc(C)c1NN

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.44
CYP3A4 P08684 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIN2B Q13224 1/20 0.43
GRIN2C Q14957 1/20 0.43
GRIN3A Q8TCU5 1/20 0.43
SIGMAR1 Q99720 1/20 0.43
CYP1A2 P05177 2/20 0.43
CYP2A6 P11509 1/20 0.43
TSHR P16473 2/20 0.42
ACHE P22303 1/20 0.42
CD44 P16070 1/20 0.42
ALDH1A1 P00352 3/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1457203 0.97 CYP3A4 (0.48) GAACYP3A4TDP1GRIN2DGRIN3B
SCHEMBL23030132 0.85 CD44 (0.52) GAACYP3A4TDP1GRIN2DGRIN3B
SCHEMBL19142147 0.83 TSHR (0.39) GAAGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL21876495 0.83 ACHE (0.48) GAAGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL1997895 0.83 GAA (0.59) GAATDP1GRIN2DGRIN3BGRIN1
SCHEMBL28057157 0.83 TRPA1 (0.50) GAATDP1GRIN2DGRIN3BGRIN1
Hydrochloric Acid SCHEMBL9545933 0.81 GAA (0.58) GAAGRIN2DGRIN3BGRIN1GRIN2A
Hydrochloric Acid SCHEMBL1809448 0.81 ACHE (0.46) GAACYP3A4TDP1GRIN2DGRIN3B
SCHEMBL11110750 0.79 LMNA (0.42) GAATDP1GRIN2DGRIN3BGRIN1
SCHEMBL3860721 0.79 TAAR1 (0.47) GAACYP3A4TDP1CYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113121382-B Metal compound material and preparation method thereof, quantum dot light emitting diode and light emitting device TCL科技集团股份有限公司 2023-08-25 CN claimed
CN-113121382-A Metal compound material and preparation method thereof, quantum dot light-emitting diode and light-emitting device TCL集团股份有限公司 2021-07-16 CN claimed
EP-0918052-B1 Improved polymeric mdi color BAYER AG (US) 2003-05-28 EP claimed
CN-111655680-B Hormone receptor modulators for the treatment of metabolic mutations and fibrotic conditions and disorders 阿德利克斯股份有限公司 2024-03-05 CN disclosed
US-11773091-B2 6-5 fused rings as C5a inhibitors CHEMOCENTRYX, INC. (US) 2023-10-03 US disclosed
US-11773091-B2 6-5 fused rings as C5a inhibitors CHEMOCENTRYX, INC. (US) 2023-10-03 US disclosed
US-11753410-B2 Hormone receptor modulators for treating metabolic mutagenic and fibrotic conditions and disorders ARDELYX, INC. (US) 2023-09-12 US disclosed
CN-113121382-B Metal compound material and preparation method thereof, quantum dot light emitting diode and light emitting device TCL科技集团股份有限公司 2023-08-25 CN disclosed
US-20230151002-A1 6-5 FUSED RINGS AS C5a INHIBITORS CHEMOCENTRYX, INC. 2023-05-18 US disclosed
EP-3630775-B1 6-5 FUSED RINGS AS C5a INHIBITORS CHEMOCENTRYX INC (US) 2022-12-14 EP disclosed
EP-3704114-B1 SPIROCYCLIC COMPOUNDS AS FARNESOID X RECEPTOR MODULATORS BRISTOL MYERS SQUIBB CO (US) 2022-11-23 EP disclosed
EP-0366328-B1 PROCESS FOR PREPARING 4-METHYLPYRAZOLES NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1993-05-19 EP disclosed
EP-0366328-A1 Process for preparing 4-methylpyrazoles NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1990-05-02 EP disclosed
US-4448961-A Substituted anilino pyrimidines ZOECON CORPORATION (US) 1984-05-15 US disclosed
US-4436744-A PHYTOPATHOGENS, SYNERGISTIC SANDOZ LTD. (CH) 1984-03-13 US disclosed
US-4411839-A α-Cyano-β-(trisubstituted phenylhydrazino)-n-ethoxycarbonylacrylamides ZOECON CORPORATION (US) 1983-10-25 US disclosed
US-4401675-A Fungicidal carbazates MONTEDISON S.P.A. (IT) 1983-08-30 US disclosed
US-4370497-A Oxidation process using tellurium oxide catalysts BARTON DEREK H R (FR) 1983-01-25 US disclosed
US-3979412-A Process for producing 3-anilino-5-pyrazolones FUJI PHOTO FILM CO., LTD. (JA) 1976-09-07 US disclosed
US-3933874-A Method for preparing of β-anilino-β-hydrazinoacrylates FUJI PHOTO FILM CO., LTD. (JA) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230151002-A1 6-5 FUSED RINGS AS C5a INHIBITORS C5AR1, C5AR2, C3AR1 GAA 4352/4885CYP3A4 1736/4885TDP1 4383/4885
US-11773091-B2 6-5 fused rings as C5a inhibitors C5AR1, C5AR2, C3AR1 GAA 4352/4885CYP3A4 1736/4885TDP1 4383/4885
US-11753410-B2 Hormone receptor modulators for treating metabolic mutagenic and fibrotic conditions and disorders NR1H4, FXR1, FXR2 GAA 2703/4885CYP3A4 327/4885TDP1 3995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.