Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12919992 | 0.86 | ALDH1A1 (0.43) | ALDH1A1MAPTL3MBTL1POLBSLC6A2 | |
| SCHEMBL11453241 | 0.79 | ALDH1A1 (0.47) | PTGS2ALDH1A1MAPTL3MBTL1POLB | |
| SCHEMBL17033348 | 0.77 | SLC6A2 (0.49) | ALDH1A1MAPTL3MBTL1POLBSLC6A2 | |
| SCHEMBL7458037 | 0.77 | CA2 (0.57) | ALDH1A1MAPTL3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL7764834 | 0.77 | MEN1 (0.50) | PTGS2ALDH1A1MAPTL3MBTL1POLB | |
| SCHEMBL14718637 | 0.77 | PDE7A (0.43) | ALDH1A1MAPTL3MBTL1POLBSLC6A2 | |
| SCHEMBL7421292 | 0.76 | MAOB (0.52) | ALDH1A1MAPTL3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL8941933 | 0.76 | ALDH1A1 (0.67) | ALDH1A1MAPTPOLBSLC6A2SLC6A4 | |
| SCHEMBL8973221 | 0.74 | PTGS2 (0.49) | PTGS2ALDH1A1MAPTL3MBTL1SLC6A2 | |
| SCHEMBL22117070 | 0.74 | RAB9A (0.73) | ALDH1A1MAPTL3MBTL1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028350-A1 | PHOTOCLEAVABLE PROTECTING GROUPS | AFFYMETRIX, INC. (US) | 2011-02-03 | — | — | US | disclosed |
| US-20100324266-A1 | Photocleavable Protecting Groups | AFFYMETRIX, INC. (US) | 2010-12-23 | — | — | US | disclosed |
| US-20090076295-A1 | PHOTOCLEAVABLE PROTECTING GROUPS | AFFYMETRIX, INC. (US) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324266-A1 | Photocleavable Protecting Groups | POLL, PCNA, ERCC4 | PTGS2 1544/4885ALDH1A1 1340/4885MAPT 2839/4885 |
| US-20090076295-A1 | PHOTOCLEAVABLE PROTECTING GROUPS | POLL, PCNA, ERCC4 | PTGS2 1544/4885ALDH1A1 1340/4885MAPT 2839/4885 |
| US-20110028350-A1 | PHOTOCLEAVABLE PROTECTING GROUPS | POLL, ERCC5, FBL | PTGS2 1473/4885ALDH1A1 2363/4885MAPT 2833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.