Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | GAK | O14976 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13757219 | 0.73 | MAPK1 (0.34) | MAPTHSD17B10MAPK1GAAGAK | |
| SCHEMBL11940152 | 0.69 | KDM4E (0.39) | MAPTKDM4EALDH1A1KMT2AADORA3 | |
| SCHEMBL7718725 | 0.68 | KDM4E (0.44) | KDM4EADORA3LMNAPKMADORA2A | |
| SCHEMBL27558227 | 0.66 | NOS1 (0.48) | MAPTHSD17B10MAPK1GAAKDM4E | |
| SCHEMBL28275637 | 0.66 | KDM4E (0.42) | KDM4EALDH1A1ADORA3LMNAPKM | |
| SCHEMBL13757232 | 0.65 | MAPK1 (0.34) | MAPTHSD17B10MAPK1GAAGAK | |
| SCHEMBL15790573 | 0.64 | ALDH1A1 (0.43) | MAPTHSD17B10KDM4EALDH1A1KMT2A | |
| SCHEMBL8992099 | 0.64 | DGAT1 (0.45) | KDM4EADORA3LMNAPKMADORA2A | |
| SCHEMBL3403505 | 0.63 | LMNA (0.38) | KDM4ENOTUMRAB9ALMNAATM | |
| SCHEMBL7057660 | 0.63 | LIMK1 (0.37) | MAPTMAPK1GAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012045114-A1 | AGENTS AND METHODS FOR TREATING HEMATOLOGIC CONDITIONS | THE UNIVERSITY OF QUEENSLAND (AU) | 2012-04-12 | — | — | WO | disclosed |