Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 3/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3685143 | 0.90 | KAT2B (0.34) | LMNAPOLBKAT2B | |
| SCHEMBL12967352 | 0.77 | MAP4K4 (0.40) | MGLLHTTKEAP1NFE2L2MAP4K1 | |
| SCHEMBL21863532 | 0.75 | MGLL (0.31) | MGLLKEAP1NFE2L2MAP4K1 | |
| SCHEMBL12539504 | 0.74 | PROKR1 (0.39) | LMNAPOLB | |
| SCHEMBL26034466 | 0.72 | PLAT (0.35) | MGLLKEAP1NFE2L2 | |
| SCHEMBL12939806 | 0.72 | MGLL (0.30) | MGLL | |
| SCHEMBL21848989 | 0.72 | MGLL (0.30) | MGLL | |
| SCHEMBL28920931 | 0.71 | ALDH1A1 (0.35) | LMNAPOLBSMN1; SMN2MGLLKEAP1 | |
| SCHEMBL31192972 | 0.71 | KDM4E (0.30) | — | |
| SCHEMBL17624319 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4655284-A1 | MICROBIOCIDAL PYRAZOLE DERIVATIVES | Syngenta Crop Protection AG (CH) | 2025-12-03 | — | — | EP | disclosed |
| EP-4643949-A2 | NICOTINAMIDE RIPK1 INHIBITORS | AbbVie Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| US-20240360099-A1 | NICOTINAMIDE RIPK1 INHIBITORS | ABBVIE INC. | 2024-10-31 | — | — | US | disclosed |
| WO-2024156886-A1 | MICROBIOCIDAL PYRAZOLE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-08-02 | — | — | WO | disclosed |
| CN-117460722-A | Nicotinamide RIPK1 inhibitors | 艾伯维公司 | 2024-01-26 | — | — | CN | disclosed |
| EP-4301744-A1 | NICOTINAMIDE RIPK1 INHIBITORS | AbbVie Inc. (US) | 2024-01-10 | — | — | EP | disclosed |
| CN-117279896-A | Amino substituted pyrido ring compounds, preparation method and application thereof | 劲方医药科技(上海)有限公司 | 2023-12-22 | — | — | CN | disclosed |
| US-11767310-B2 | Nicotinamide RIPK1 inhibitors | ABBVIE INC. (US) | 2023-09-26 | — | — | US | disclosed |
| US-11767310-B2 | Nicotinamide RIPK1 inhibitors | ABBVIE INC. (US) | 2023-09-26 | — | — | US | disclosed |
| WO-2023143482-A1 | 2-AMINOPYRIMIDINE COMPOUND OR SALT, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海辉启生物医药科技有限公司 | 2023-08-03 | — | — | WO | disclosed |
| US-20230127127-A1 | NICOTINAMIDE RIPK1 INHIBITORS | ABBVIE INC. | 2023-04-27 | — | — | US | disclosed |
| US-20230127127-A1 | NICOTINAMIDE RIPK1 INHIBITORS | ABBVIE INC. | 2023-04-27 | — | — | US | disclosed |
| WO-2023018643-A1 | NICOTINAMIDE RIPK1 INHIBITORS | ABBVIE INC. (US) | 2023-02-16 | — | — | WO | disclosed |
| WO-2023018643-A1 | NICOTINAMIDE RIPK1 INHIBITORS | ABBVIE INC. (US) | 2023-02-16 | — | — | WO | disclosed |
| WO-2022214044-A1 | AMINE-SUBSTITUTED PYRIDINE FUSED RING COMPOUNDS, PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2022-10-13 | — | — | WO | disclosed |
| EP-2445909-B1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INT (DE) | 2013-11-13 | — | — | EP | disclosed |
| US-20120252817-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-10-04 | — | — | US | disclosed |
| US-20120252817-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240360099-A1 | NICOTINAMIDE RIPK1 INHIBITORS | RIPK1, RIPK2, RIPK4 | LMNA 1936/4885POLB 2859/4885SMN1; SMN2 3077/4885 |
| US-20120252817-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES | ARG1, COL14A1, HPGDS | LMNA 3234/4885POLB 4566/4885SMN1; SMN2 3967/4885 |
| US-20230127127-A1 | NICOTINAMIDE RIPK1 INHIBITORS | RIPK1, RIPK2, RIPK4 | LMNA 1936/4885POLB 2859/4885SMN1; SMN2 3077/4885 |
| US-11767310-B2 | Nicotinamide RIPK1 inhibitors | RIPK1, RIPK2, RIPK4 | LMNA 1936/4885POLB 2859/4885SMN1; SMN2 3077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.