Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 8/20 | 0.37 |
| ▸ | BRD1 | O95696 | 6/20 | 0.37 |
| ▸ | BRPF3 | Q9ULD4 | 5/20 | 0.37 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10022422 | 0.85 | BRPF1 (0.43) | ENPP3CDC7IMPDH2IMPDH1BRPF1 | |
| SCHEMBL10053515 | 0.76 | BRPF1 (0.45) | ENPP3CDC7BRPF1BRD1BRPF3 | |
| SCHEMBL27969722 | 0.75 | ENPP3 (0.42) | ENPP3CDC7IMPDH2IMPDH1BRPF1 | |
| SCHEMBL28265765 | 0.75 | ENPP3 (0.42) | ENPP3CDC7IMPDH2IMPDH1BRPF1 | |
| SCHEMBL1113031 | 0.74 | XDH (0.41) | ENPP3CDC7BRPF1BRD1BRPF3 | |
| SCHEMBL11689499 | 0.73 | KMT2A (0.60) | ENPP3ALB | |
| SCHEMBL4617249 | 0.73 | KDM4E (0.60) | ALBNTRK1 | |
| SCHEMBL6263704 | 0.72 | BRPF1 (0.42) | ENPP3CDC7BRPF1BRD1BRPF3 | |
| SCHEMBL1338266 | 0.72 | CDC7 (0.40) | ENPP3CDC7IMPDH2IMPDH1BRPF1 | |
| SCHEMBL10066950 | 0.72 | CYP2A6 (0.44) | ENPP3CDC7BRPF1BRD1BRPF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120252853-A1 | Positive allosteric modulators of nicotinic acetylcholine receptor | H. LUNDBECK A/S (DK) | 2012-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120252853-A1 | Positive allosteric modulators of nicotinic acetylcholine receptor | CHRNG, CHRNA7, CHRNA2 | ENPP3 555/4885CDC7 2116/4885IMPDH2 3077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.