Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | XDH | P47989 | 4/20 | 0.48 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | BLVRB | P30043 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867920 | 0.88 | RAB9A (0.61) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL2009745 | 0.79 | RAB9A (0.59) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL438271 | 0.78 | XDH (0.68) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL21156699 | 0.77 | RAB9A (0.69) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL2011167 | 0.77 | RAB9A (0.79) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL17629243 | 0.77 | RAB9A (0.67) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL17629244 | 0.77 | RAB9A (0.67) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL27795018 | 0.76 | RAB9A (0.56) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL12970049 | 0.76 | RAB9A (0.77) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL2069278 | 0.76 | RAB9A (1.00) | RAB9ASMN1; SMN2KDM4ENPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012131590-A1 | AN IMPROVED PROCESS FOR PREPARATION OF FEBUXOSTAT AND ITS POLYMORPHIC CRYSTALLINE FORM C THEREOF | SANDOZ AG (CH) | 2012-10-04 | — | — | WO | disclosed |