Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2193456 | 0.88 | MEN1 (0.35) | TDP1MEN1LMNACYP3A4CYP2C9 | |
| SCHEMBL4698289 | 0.85 | ALDH1A1 (0.35) | TDP1MEN1LMNACYP3A4CYP2C9 | |
| SCHEMBL917125 | 0.84 | MEN1 (0.36) | TDP1MEN1LMNACYP3A4CYP2C9 | |
| SCHEMBL4698309 | 0.84 | PRKCA (0.36) | TDP1MEN1LMNACYP3A4CYP2C9 | |
| SCHEMBL1764576 | 0.83 | KMT2A (0.49) | TDP1MEN1LMNACYP3A4CYP2C9 | |
| SCHEMBL12972246 | 0.83 | KMT2A (0.35) | TDP1MEN1LMNACYP3A4CYP2C9 | |
| SCHEMBL21814412 | 0.83 | TDP1 (0.35) | TDP1MEN1LMNACYP3A4CYP2C9 | |
| SCHEMBL4698290 | 0.82 | MAPT (0.35) | TDP1MEN1LMNACYP3A4CYP2C9 | |
| SCHEMBL4701760 | 0.80 | MAPT (0.42) | TDP1MEN1LMNACYP3A4KMT2A | |
| SCHEMBL15218253 | 0.80 | ALDH1A1 (0.38) | LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919859-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | Xenoport, Inc. (US) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007002013-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2007-01-04 | — | — | WO | disclosed |