Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4701760 | 0.92 | MAPT (0.42) | MAPTLMNAKMT2ACYP3A4TDP1 | |
| SCHEMBL4698289 | 0.89 | ALDH1A1 (0.35) | LMNAKMT2ACYP3A4TDP1MEN1 | |
| SCHEMBL917125 | 0.84 | MEN1 (0.36) | LMNAKMT2ACYP3A4TDP1MEN1 | |
| SCHEMBL3109237 | 0.82 | DGKA (0.40) | MAPTLMNAKMT2ATDP1NLRP3 | |
| SCHEMBL4699686 | 0.82 | TDP1 (0.35) | LMNAKMT2ACYP3A4TDP1MEN1 | |
| SCHEMBL2193456 | 0.82 | MEN1 (0.35) | LMNAKMT2ACYP3A4TDP1MEN1 | |
| SCHEMBL12972246 | 0.81 | KMT2A (0.35) | LMNAKMT2ACYP3A4TDP1MEN1 | |
| SCHEMBL4696895 | 0.80 | DGKA (0.38) | MAPTLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL4698358 | 0.80 | PRKCA (0.39) | MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL4698309 | 0.79 | PRKCA (0.36) | LMNAKMT2ACYP3A4TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919859-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | Xenoport, Inc. (US) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007002013-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2007-01-04 | — | — | WO | disclosed |