SCHEMBL12979544

SCHEMBL12979544

CCCCC(CN)C(C)C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
OPRM1 P35372 1/20 0.34
CA2 P00918 3/20 0.33
CA1 P00915 2/20 0.33
DNM1 Q05193 2/20 0.31
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8117589 0.82 CA2 (0.37) ALDH1A1TDP1OPRM1CA2CA1
SCHEMBL4857794 0.81 ALDH1A1 (0.54) ALDH1A1TDP1OPRM1CA2CA1
SCHEMBL18124690 0.81 ALDH1A1 (0.54) ALDH1A1TDP1OPRM1CA2CA1
SCHEMBL22681516 0.77 TSHR (0.32) ALDH1A1
SCHEMBL23015677 0.75 OPRM1 (0.50) ALDH1A1TDP1OPRM1CA1DNM1
SCHEMBL29035274 0.74 OPRM1 (0.39) OPRM1CA2DNM1
SCHEMBL17903494 0.73 OPRM1 (0.48) ALDH1A1TDP1OPRM1DNM1
SCHEMBL21925359 0.72 DNM1 (0.36) ALDH1A1TDP1OPRM1CA2CA1
SCHEMBL4656057 0.70 DNM1 (0.43) ALDH1A1TDP1OPRM1CA2CA1
SCHEMBL18638254 0.70 DNM1 (0.35) ALDH1A1TDP1OPRM1CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8729185-B2 Method for producing 2-cyanoethyl group-containing organic compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-20 US disclosed
US-20120259067-A1 Method for Producing 2-Cyanoethyl Group-Containing Organic Compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-10-11 US disclosed