Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PAM | P19021 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL616258 | 0.94 | DGKA (0.64) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL7282921 | 0.94 | DGKA (0.59) | DGKAPRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL129849 | 0.94 | DGKA (0.64) | DGKAPRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL2485452 | 0.92 | DGKA (0.68) | DGKAPRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL7841880 | 0.92 | DGKA (0.68) | DGKAPRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL11249237 | 0.92 | DGKA (0.68) | DGKAPRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL129577 | 0.92 | DGKA (0.68) | DGKAPRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL8895425 | 0.92 | DGKA (0.68) | DGKAPRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL8453125 | 0.92 | DGKA (0.68) | DGKAPRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL7839840 | 0.92 | DGKA (0.68) | DGKAPRSS1PRSS2PRSS3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 297 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | PHARMACIA AND UPJOHN COMPANY LLC | 2005-09-08 | — | — | US | claimed |
| WO-2005037797-A1 | SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | claimed |
| CN-115192470-B | Oily composition | 宝丽化成工业有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-113693965-B | External preparation for skin for improving wrinkles | 宝丽化成工业有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-115192470-A | Oily composition | 宝丽化成工业有限公司 | 2022-10-18 | — | — | CN | disclosed |
| EP-4008304-A2 | EXTERNAL PREPARATION FOR SKIN FOR WRINKLE IMPROVEMENT | Pola Chemical Industries Inc. (JP) | 2022-06-08 | — | — | EP | disclosed |
| EP-3476381-B1 | EXTERNAL PREPARATION FOR SKIN FOR WRINKLE IMPROVEMENT | POLA CHEM IND INC (JP) | 2021-12-22 | — | — | EP | disclosed |
| CN-113693965-A | External preparation for skin for improving wrinkles | 宝丽化成工业有限公司 | 2021-11-26 | — | — | CN | disclosed |
| CN-109310585-B | External preparation for skin for improving wrinkles | 宝丽化成工业有限公司 | 2021-10-29 | — | — | CN | disclosed |
| US-20210030631-A1 | EXTERNAL PREPARATION FOR SKIN FOR WRINKLE IMPROVEMENT | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2021-02-04 | — | — | US | disclosed |
| US-20200368131-A1 | OIL-BASED COMPOSITION | POLA CHEM IND INC (JP) | 2020-11-26 | — | — | US | disclosed |
| EP-0103278-A2 | Anthraquinone dyes and their use | BASF Aktiengesellschaft (DE) | 1984-03-21 | — | — | EP | disclosed |
| US-4386086-A | ENOL DERIVATIVES OF 2-ARYL-1,3-INDANDIONES | UNION CARBIDE CORPORATION (US) | 1983-05-31 | — | — | US | disclosed |
| EP-0004026-B1 | HYDROLYTICALLY STABLE ORTHO-ALKYLATED PHENYL PHOSPHONITES AND STABILIZED COMPOSITIONS | CIBA-GEIGY AG (CH) | 1982-05-05 | — | — | EP | disclosed |
| US-4233207-A | STABILIZING POLYMERS AGAINST OXIDATION, HEAT, AND RADIATION | CIBA-GEIGY CORPORATION (US) | 1980-11-11 | — | — | US | disclosed |
| EP-0008540-A2 | 2-aryl-1,3-indandione derivatives and compositions comprising them for controlling ectoparasitic acarina | UNION CARBIDE CORPORATION (US) | 1980-03-05 | — | — | EP | disclosed |
| EP-0004026-A1 | Hydrolytically stable ortho-alkylated phenyl phosphonites and stabilized compositions | CIBA-GEIGY AG (CH) | 1979-09-19 | — | — | EP | disclosed |
| US-4136100-A | BLUE-VIOLET TO GREEN-BLUE DYEINGS ON CELLULOSE TEXTILES | BASF AKTIENGESELLSCHAFT (DE) | 1979-01-23 | — | — | US | disclosed |
| US-4104043-A | Esters of 3-hydroxyindone compounds as herbicides and miticides | UNION CARBIDE CORPORATION (US) | 1978-08-01 | — | — | US | disclosed |
| US-4091006-A | MITICIDES AND HERBICIDES | UNION CARBIDE CORPORATION (US) | 1978-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210030631-A1 | EXTERNAL PREPARATION FOR SKIN FOR WRINKLE IMPROVEMENT | F12, CUTA, SQLE | DGKA 1567/4885PRSS1 1122/4885PRSS2 1986/4885 |
| US-20200368131-A1 | OIL-BASED COMPOSITION | CUTA, EBP, LIPA | DGKA 418/4885PRSS1 2208/4885PRSS2 2130/4885 |
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | IL4, ARG2, CASP4 | DGKA 4757/4885PRSS1 588/4885PRSS2 474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.