SCHEMBL13005509 — predicted protein targets

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	SLC6A4	P31645	15/20	0.47

▸	SLC6A2	P23975	11/20	0.47

▸	CETP	P11597	1/20	0.43

▸	SLC6A3	Q01959	10/20	0.41

▸	HTR2A	P28223	7/20	0.39

▸	KCNH2	Q12809	2/20	0.37

▸	CYP2D6	P10635	3/20	0.35

▸	RIPK1	Q13546	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL13061095	0.93	SLC6A4 (0.48)	SLC6A4SLC6A2CETPSLC6A3HTR2A
SCHEMBL13005616	0.89	BCHE (0.40)	SLC6A4SLC6A2CETPSLC6A3HTR2A
SCHEMBL13005641	0.85	SLC6A4 (0.41)	SLC6A4SLC6A2CETPSLC6A3HTR2A
SCHEMBL13005518	0.84	CETP (0.40)	SLC6A4SLC6A2CETPSLC6A3HTR2A
SCHEMBL13005520	0.82	LMNA (0.37)	SLC6A4SLC6A2CETPSLC6A3
SCHEMBL13005504	0.82	ALDH1A1 (0.36)	SLC6A2CETPSLC6A3RIPK1
SCHEMBL13005507	0.82	TAAR1 (0.34)	CETPCYP2D6
SCHEMBL13005500	0.82	GABRA1 (0.39)	CETP
SCHEMBL13005522	0.82	CETP (0.36)	CETP
SCHEMBL13005530	0.82	TAAR1 (0.48)	CETPHTR2ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-7851637-B2	Compounds and methods for inhibiting the interaction of BCL proteins with binding partners	INFINITY PHARMACEUTICALS, INC. (US)	2010-12-14	—	—	US	disclosed