SCHEMBL130135

SCHEMBL130135

CC/C=C\C/C=C\C/C=C\CCCCCCCCOCCCCCCCC/C=C\C/C=C\C/C=C\CC

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
F7 P08709 2/20 0.53
F3 P13726 2/20 0.53
MAPT P10636 2/20 0.53
CYP19A1 P11511 2/20 0.53
OXER1 Q8TDS5 1/20 0.53
KDM4E B2RXH2 1/20 0.53
MEN1 O00255 1/20 0.53
FFAR1 O14842 1/20 0.53
NR1I2 O75469 1/20 0.53
LMNA P02545 1/20 0.53
PLA2G1B P04054 1/20 0.53
CYP3A4 P08684 1/20 0.53
HPGD P15428 1/20 0.53
ALOX15 P16050 1/20 0.53
PTGS1 P23219 1/20 0.53
PTGS2 P35354 1/20 0.53
PPARG P37231 1/20 0.53
RECQL P46063 1/20 0.53
BLM P54132 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17107448 0.93 LPAR2 (0.57) ALDH1A1F7F3MAPTCYP19A1
SCHEMBL13491427 0.92 ALDH1A1 (0.53) ALDH1A1F7F3MAPTCYP19A1
Sulfuric Acid SCHEMBL17956299 0.89 ALDH1A1 (0.53) ALDH1A1F7F3MAPTCYP19A1
SCHEMBL12975615 0.88 ALDH1A1 (0.51) ALDH1A1F7F3MAPTCYP19A1
SCHEMBL23017141 0.88 ALDH1A1 (0.44) ALDH1A1F7F3MAPTCYP19A1
SCHEMBL931447 0.88 ALDH1A1 (0.44) ALDH1A1F7F3MAPTCYP19A1
SCHEMBL29073201 0.87 LPAR2 (0.52) LPAR2LPAR3LPAR1
SCHEMBL12474184 0.87 ALDH1A1 (0.58) ALDH1A1
SCHEMBL6261092 0.87 ALDH1A1 (0.58) ALDH1A1
SCHEMBL20548251 0.87 LPAR2 (0.52) LPAR2LPAR3LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 326 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117298034-A Drug-loaded microemulsion-nanogel composite preparation for treating children eczema and preparation method and application thereof 临沂大学 2023-12-29 CN claimed
CN-117379342-A Solid powder cosmetic 株式会社常盘 2024-01-12 CN disclosed
CN-117298034-A Drug-loaded microemulsion-nanogel composite preparation for treating children eczema and preparation method and application thereof 临沂大学 2023-12-29 CN disclosed
CN-111741741-B Solid powder cosmetic 株式会社常盘 2023-11-21 CN disclosed
US-11382884-B2 Method for reducing lung infection Respirion Pharmaceuticals Pty Ltd (CA) 2022-07-12 US disclosed
EP-3641750-A1 METHOD FOR REDUCING LUNG INFECTION Respirion Pharmaceuticals Pty Ltd (AU) 2020-04-29 EP disclosed
US-20200108033-A1 METHOD FOR REDUCING LUNG INFECTION Respirion Pharmaceuticals Pty Ltd (AU) 2020-04-09 US disclosed
US-10561649-B2 Pharmaceutical combination of opioid and prostaglandin compound SUCAMPO AG (CH) 2020-02-18 US disclosed
WO-2018232453-A1 METHOD FOR REDUCING LUNG INFECTION Respirion Pharmaceuticals Pty Ltd (AU) 2018-12-27 WO disclosed
US-20180311233-A1 PHARMACEUTICAL COMBINATION OF OPIOID AND PROSTAGLANDIN COMPOUND SUCAMPO AG (CH) 2018-11-01 US disclosed
US-20010056104-A1 Treatment of ocular hypertension and glaucoma SUCAMPO, A.G. (CH) 2001-12-27 US disclosed
EP-0736591-B1 Lubricating oil additive, lubricating oil and working fluid for refrigerators JAPAN ENERGY CORP (JP) 2001-12-12 EP disclosed
US-20010034355-A1 Treatment of ocular hypertension SUCAMPO, AG (CH) 2001-10-25 US disclosed
WO-2001076593-A2 BILE SECRETION PROMOTING COMPOSITION A 15-KETO PROSTAGLANDIN SUCAMPO AG (CH) 2001-10-18 WO disclosed
WO-2001068072-A2 COMPOSITION FOR USE IN TREATMENT OF OCULAR HYPERTENSION AND GLAUCOMA SUCAMPO AG (CH) 2001-09-20 WO disclosed
WO-2001027099-A2 BICYCLIC COMPOUNDS COMPOSITION AND METHOD FOR STABILIZING THE SAME SUCAMPO, A.G. (CH) 2001-04-19 WO disclosed
WO-2001005388-A2 USE OF A FATTY DERIVATIVE FOR THE TREATMENT OF EXTERNAL SECRETIONDISORDERS SUCAMPO, A.G. (CH) 2001-01-25 WO disclosed
WO-2000077302-A1 USE OF LONG-CHAIN FATTY ETHERS NOPCO PAPER TECHNOLOGY HOLDING AS (NO) 2000-12-21 WO disclosed
US-5744053-A COMPRISING PARTIALLY ETHERIFIED POLYHYDRIC ALCOHOL AND PHOSPHATE COMPOUND JAPAN ENERGY CORPORATION (JP) 1998-04-28 US disclosed
EP-0736591-A2 Lubricating oil additive, lubricating oil and working fluid for refrigerators JAPAN ENERGY CORPORATION (JP) 1996-10-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010034355-A1 Treatment of ocular hypertension PTGIS, PTGIR, PTGS1 ALDH1A1 216/4885F7 3341/4885F3 2267/4885
US-20180311233-A1 PHARMACEUTICAL COMBINATION OF OPIOID AND PROSTAGLANDIN COMPOUND OPRK1, OPRM1, OPRD1 ALDH1A1 498/4885F7 1534/4885F3 2771/4885
US-10561649-B2 Pharmaceutical combination of opioid and prostaglandin compound OPRK1, OPRM1, OPRD1 ALDH1A1 498/4885F7 1534/4885F3 2771/4885
US-20010056104-A1 Treatment of ocular hypertension and glaucoma PTGIS, PTGIR, PTGS1 ALDH1A1 422/4885F7 2498/4885F3 2406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.