Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 6/20 | 0.34 |
| ▸ | IDO1 | P14902 | 4/20 | 0.33 |
| ▸ | AGXT | P21549 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15667983 | 0.80 | NR3C1 (0.36) | NR3C1RIPK1DPP4PKMHTR2A | |
| SCHEMBL4404016 | 0.79 | RIPK1 (0.46) | NR3C1RIPK1IDO1AGXTDPP4 | |
| SCHEMBL16425421 | 0.78 | TAAR1 (0.35) | RIPK1HTR2AHTR2C | |
| SCHEMBL12870200 | 0.78 | NR3C1 (0.39) | NR3C1RIPK1HTR2ACA3CA6 | |
| SCHEMBL322033 | 0.77 | GABRA1 (0.39) | NR3C1RIPK1DPP4PKMHTR2A | |
| SCHEMBL15107027 | 0.76 | CA3 (0.45) | RIPK1CA3CA6CA5ACA9 | |
| SCHEMBL19544101 | 0.76 | NR3C1 (0.45) | NR3C1RIPK1HTR2ANR3C2SLC6A4 | |
| SCHEMBL21685661 | 0.76 | ALDH1A1 (0.45) | RIPK1IDO1AGXTSLC6A4 | |
| SCHEMBL21767395 | 0.76 | NR3C1 (0.38) | NR3C1RIPK1IDO1AGXTDPP4 | |
| SCHEMBL31072009 | 0.76 | NR3C1 (0.38) | NR3C1RIPK1IDO1AGXTDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331348-A1 | TROPANE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331348-A1 | TROPANE DERIVATIVES USEFUL AS PESTICIDES | DDT, ACHE, TPM3 | NR3C1 2239/4885RIPK1 3814/4885IDO1 515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.