SCHEMBL13023908

SCHEMBL13023908

Cc1cc(C)c(N2c3ccccc3Cc3c2oc2ccccc32)c(C)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.36
MAPT P10636 2/20 0.36
RAB9A P51151 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
NFKB1 P19838 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
SIGMAR1 Q99720 1/20 0.33
PIK3CD O00329 2/20 0.33
PIK3CA P42336 2/20 0.33
PIK3CB P42338 2/20 0.33
PIK3CG P48736 2/20 0.33
ALDH1A1 P00352 3/20 0.32
LMNA P02545 1/20 0.32
PRKDC P78527 2/20 0.32
MTOR P42345 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13022816 0.90 NPSR1 (0.36) L3MBTL1MAPTNPC1NPSR1MEN1
SCHEMBL13023953 0.89 NPSR1 (0.40) L3MBTL1MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL13023956 0.88 L3MBTL1 (0.42) L3MBTL1MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL13023843 0.86 LMNA (0.36) L3MBTL1MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL13023903 0.86 GLA (0.38) L3MBTL1MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL13022834 0.82 NPSR1 (0.34) MAPTNPC1NPSR1MEN1KMT2A
SCHEMBL13023955 0.81 RAB9A (0.33) L3MBTL1MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL13022107 0.80 PRKDC (0.36) MAPTNPC1KMT2APRKDCKDM4E
SCHEMBL13022871 0.80 NPSR1 (0.39) L3MBTL1MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL13065779 0.80 RAB9A (0.37) L3MBTL1MAPTRAB9ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 L3MBTL1 250/4885MAPT 2367/4885RAB9A 2397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.