SCHEMBL13023903

SCHEMBL13023903

COc1cc(C)cc(OC)c1N1c2ccccc2Cc2c1oc1ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.38
BRAF P15056 1/20 0.37
MAPT P10636 5/20 0.36
KDM4E B2RXH2 4/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
LMNA P02545 3/20 0.36
ALDH1A1 P00352 3/20 0.36
TSHR P16473 2/20 0.36
HSD17B10 Q99714 2/20 0.36
TP53 P04637 1/20 0.36
HPGD P15428 1/20 0.36
MAPK1 P28482 1/20 0.36
GAA P10253 1/20 0.35
NPC1 O15118 2/20 0.35
HTR1A P08908 1/20 0.35
HTR7 P34969 1/20 0.35
HTR6 P50406 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.34
DRD2 P14416 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13023945 0.90 MAPT (0.38) GLABRAFMAPTKDM4EMEN1
SCHEMBL13023948 0.88 CRHBP (0.40) GLABRAFMAPTKDM4EMEN1
SCHEMBL13023849 0.88 MEN1 (0.38) GLABRAFMAPTKDM4EMEN1
SCHEMBL13023908 0.86 L3MBTL1 (0.36) MAPTKDM4EMEN1KMT2ALMNA
SCHEMBL13023947 0.82 L3MBTL1 (0.35) GLABRAFMAPTKDM4EMEN1
SCHEMBL13022789 0.80 MEN1 (0.47) GLAMAPTKDM4EMEN1KMT2A
SCHEMBL13023341 0.79 TUBB4A (0.46) MAPTKMT2ALMNAALDH1A1HSD17B10
SCHEMBL13023918 0.78 MEN1 (0.40) GLAMAPTKDM4EMEN1KMT2A
SCHEMBL13023843 0.78 LMNA (0.36) MAPTMEN1KMT2ALMNAALDH1A1
SCHEMBL13022816 0.77 NPSR1 (0.36) MAPTKDM4EMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 GLA 3030/4885BRAF 2136/4885MAPT 2367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.