SCHEMBL13023955

SCHEMBL13023955

Cc1cc(C)c(N2c3ccccc3COc3c2oc2ccccc32)c(C)c1

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MAPT P10636 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
NPC1 O15118 1/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MPO P05164 1/20 0.33
PIK3CD O00329 1/20 0.32
PIK3CA P42336 1/20 0.32
PIK3CB P42338 1/20 0.32
PIK3CG P48736 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13022877 0.91 NPSR1 (0.35) RAB9ASMN1; SMN2MAPTNPC1NPSR1
SCHEMBL13023913 0.87 LMNA (0.34) RAB9ASMN1; SMN2MAPTL3MBTL1NPC1
SCHEMBL13023947 0.86 L3MBTL1 (0.35) RAB9ASMN1; SMN2MAPTL3MBTL1NPC1
SCHEMBL13022886 0.82 NPSR1 (0.33) NPSR1
SCHEMBL13022163 0.81 PRKDC (0.33) RAB9ANPC1
SCHEMBL13023908 0.81 L3MBTL1 (0.36) RAB9ASMN1; SMN2MAPTL3MBTL1NPC1
SCHEMBL13023953 0.80 NPSR1 (0.40) RAB9ASMN1; SMN2MAPTL3MBTL1NPC1
SCHEMBL13023904 0.79 PIK3CD (0.33) SMN1; SMN2MAPTPIK3CDPIK3CAPIK3CB
SCHEMBL13023927 0.79 MAPT (0.35) RAB9ASMN1; SMN2MAPTL3MBTL1NPC1
SCHEMBL13023920 0.79 LMNA (0.35) RAB9ASMN1; SMN2MAPTL3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 RAB9A 2397/4885SMN1; SMN2 1804/4885MAPT 2367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.