SCHEMBL13023920

SCHEMBL13023920

COc1cc(C)ccc1N1c2ccccc2COc2c1oc1ccccc21

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.35
ALDH1A1 P00352 4/20 0.35
MEN1 O00255 6/20 0.35
KMT2A Q03164 6/20 0.35
MAPT P10636 5/20 0.34
GAA P10253 1/20 0.34
GLA P06280 1/20 0.34
THRB P10828 1/20 0.34
NPC1 O15118 1/20 0.33
KDM4E B2RXH2 2/20 0.33
HPGD P15428 2/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
MAOB P27338 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13022845 0.88 MEN1 (0.43) LMNAALDH1A1MEN1KMT2AMAPT
SCHEMBL13023947 0.88 L3MBTL1 (0.35) LMNAALDH1A1MEN1KMT2AMAPT
SCHEMBL13023913 0.87 LMNA (0.34) LMNAALDH1A1MEN1KMT2AMAPT
SCHEMBL13022127 0.85 MEN1 (0.43) LMNAALDH1A1MEN1KMT2AMAPT
SCHEMBL13023927 0.83 MAPT (0.35) ALDH1A1MEN1KMT2AMAPTNPC1
SCHEMBL13023849 0.83 MEN1 (0.38) LMNAALDH1A1MEN1KMT2AMAPT
SCHEMBL13023918 0.82 MEN1 (0.40) LMNAALDH1A1MEN1KMT2AMAPT
SCHEMBL13023844 0.81 ADCY2 (0.37) LMNAALDH1A1MEN1KMT2AMAPT
SCHEMBL13023922 0.80 KMT2A (0.43) LMNAALDH1A1MEN1KMT2AMAPT
SCHEMBL13023919 0.80 MEN1 (0.41) LMNAALDH1A1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 LMNA 1808/4885ALDH1A1 579/4885MEN1 725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.