SCHEMBL13023918

SCHEMBL13023918

COc1cc(C)ccc1N1c2ccccc2CCc2c1oc1ccccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.40
KMT2A Q03164 6/20 0.40
MAPT P10636 4/20 0.37
NPC1 O15118 3/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
RAB9A P51151 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
GLA P06280 1/20 0.36
KDM4E B2RXH2 4/20 0.36
ALDH1A1 P00352 4/20 0.36
HSD17B10 Q99714 3/20 0.36
GAA P10253 2/20 0.36
THRB P10828 2/20 0.36
USP2 O75604 1/20 0.36
POLB P06746 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13023922 0.94 KMT2A (0.43) MEN1KMT2AMAPTNPC1L3MBTL1
SCHEMBL13023849 0.90 MEN1 (0.38) MEN1KMT2AMAPTNPC1GLA
SCHEMBL13022844 0.88 MEN1 (0.46) MEN1KMT2AMAPTNPC1L3MBTL1
SCHEMBL13023945 0.88 MAPT (0.38) MEN1KMT2AMAPTNPC1L3MBTL1
SCHEMBL13023911 0.86 NPSR1 (0.40) MEN1KMT2AMAPTNPC1L3MBTL1
SCHEMBL13022129 0.85 MEN1 (0.46) MEN1KMT2AMAPTNPC1L3MBTL1
SCHEMBL13023924 0.83 MAPT (0.37) KMT2AMAPTNPC1L3MBTL1RAB9A
SCHEMBL13022842 0.82 MEN1 (0.45) MEN1KMT2AMAPTNPC1L3MBTL1
SCHEMBL13023948 0.82 CRHBP (0.40) MEN1KMT2AMAPTNPC1L3MBTL1
SCHEMBL13023920 0.82 LMNA (0.35) MEN1KMT2AMAPTNPC1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 MEN1 725/4885KMT2A 2070/4885MAPT 2367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.