SCHEMBL13023945

SCHEMBL13023945

COc1cc(C)cc(OC)c1N1c2ccccc2CCc2c1oc1ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.38
NPC1 O15118 3/20 0.38
RAB9A P51151 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
GLA P06280 1/20 0.37
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
BRAF P15056 1/20 0.36
KDM4E B2RXH2 4/20 0.36
ALDH1A1 P00352 4/20 0.36
LMNA P02545 3/20 0.36
TSHR P16473 2/20 0.36
HSD17B10 Q99714 2/20 0.36
TP53 P04637 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13023948 0.94 CRHBP (0.40) MAPTNPC1RAB9ANPSR1NFKB1
SCHEMBL13023903 0.90 GLA (0.38) MAPTNPC1RAB9ANPSR1NFKB1
SCHEMBL13023918 0.88 MEN1 (0.40) MAPTNPC1RAB9ANPSR1NFKB1
SCHEMBL13023953 0.86 NPSR1 (0.40) MAPTNPC1RAB9ANPSR1NFKB1
SCHEMBL13023922 0.82 KMT2A (0.43) MAPTNPC1RAB9ANPSR1NFKB1
SCHEMBL13023947 0.81 L3MBTL1 (0.35) MAPTNPC1RAB9ASMN1; SMN2L3MBTL1
SCHEMBL13023956 0.81 L3MBTL1 (0.42) MAPTNPC1RAB9ANPSR1NFKB1
SCHEMBL13023441 0.80 ALDH1A1 (0.42) MAPTSMN1; SMN2L3MBTL1MEN1KMT2A
SCHEMBL13022844 0.80 MEN1 (0.46) MAPTNPC1RAB9ANPSR1SMN1; SMN2
SCHEMBL13023911 0.78 NPSR1 (0.40) MAPTNPC1RAB9ANPSR1NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 MAPT 2367/4885NPC1 2394/4885RAB9A 2397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.