SCHEMBL13023948

SCHEMBL13023948

COc1cc(C)cc(OC)c1N1c2ccccc2CCCc2c1oc1ccccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHBP P24387 1/20 0.40
CRHR2 Q13324 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
NPSR1 Q6W5P4 3/20 0.38
KDM4E B2RXH2 2/20 0.38
GAA P10253 1/20 0.38
BRAF P15056 1/20 0.37
ALDH1A1 P00352 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
MAPT P10636 1/20 0.36
NFKB1 P19838 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PDE4A P27815 1/20 0.36
PDE4B Q07343 1/20 0.36
PDE4C Q08493 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13023945 0.94 MAPT (0.38) CRHBPCRHR2MEN1KMT2ANPC1
SCHEMBL13023922 0.88 KMT2A (0.43) CRHBPCRHR2MEN1KMT2ANPC1
SCHEMBL13023903 0.88 GLA (0.38) MEN1KMT2ANPC1RAB9ANPSR1
SCHEMBL13023956 0.88 L3MBTL1 (0.42) MEN1KMT2ANPC1RAB9ANPSR1
SCHEMBL13023953 0.82 NPSR1 (0.40) MEN1KMT2ANPC1RAB9ANPSR1
SCHEMBL13023918 0.82 MEN1 (0.40) MEN1KMT2ANPC1RAB9ANPSR1
SCHEMBL13023459 0.81 CRHBP (0.45) CRHBPCRHR2MEN1KMT2AGAA
SCHEMBL13022842 0.81 MEN1 (0.45) CRHBPCRHR2MEN1KMT2ANPC1
SCHEMBL13023914 0.80 ALDH1A1 (0.39) MEN1KMT2ANPC1RAB9ANPSR1
SCHEMBL13023947 0.80 L3MBTL1 (0.35) MEN1KMT2ANPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 CRHBP 4036/4885CRHR2 1139/4885MEN1 725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.