SCHEMBL13024593

SCHEMBL13024593

CN(C)c1ccc2c(-c3c(Cl)cc(C(=O)NCCc4ccc(-c5c6ccc(=O)cc-6oc6cc(O)ccc56)c(C(=O)O)c4)c(Cl)c3C(=O)O)c3ccc(=[N+](C)C)cc-3oc2c1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ CA9 Q16790 8/20 0.47
▸ CA1 P00915 7/20 0.47
▸ CA2 P00918 7/20 0.47
▸ CA12 O43570 5/20 0.47
▸ CA14 Q9ULX7 3/20 0.47
▸ CA7 P43166 2/20 0.47
▸ P2RY6 Q15077 1/20 0.45
▸ USP2 O75604 1/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ HTR3A P46098 1/20 0.44
▸ SLC5A2 P31639 2/20 0.43
▸ ESR1 P03372 1/20 0.42
▸ ALB P02768 1/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ THRB P10828 1/20 0.41
▸ RECQL P46063 1/20 0.41
▸ BLM P54132 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13041605 0.93 CA9 (0.47) CA9CA1CA2CA12CA14
SCHEMBL10293931 0.93 CA9 (0.47) CA9CA1CA2CA12CA14
SCHEMBL13024588 0.92 P2RY6 (0.54) CA9CA1CA2CA12P2RY6
SCHEMBL14415021 0.91 CA9 (0.47) CA9CA1CA2CA12CA14
SCHEMBL10137968 0.91 ESR1 (0.48) CA9CA1CA2CA12CA14
SCHEMBL14115544 0.90 CA9 (0.46) CA9CA1CA2CA12CA14
SCHEMBL13024600 0.89 ESR1 (0.47) CA9CA1CA2CA12CA14
SCHEMBL13041602 0.87 P2RY6 (0.48) CA9CA1CA2CA12CA14
SCHEMBL13024595 0.87 ESR1 (0.48) CA9CA1CA2CA12CA14
SCHEMBL13041604 0.85 MEN1 (0.45) CA9CA1CA2CA12CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100280246-A1 ENERGY TRANSFER DYES WITH ENHANCED FLUORESCENCE APPLERA CORPORATION (US) 2010-11-04 — — US disclosed
US-7595162-B2 Methods of labeling polynucleotides with energy transfer dyes APPLIED BIOSYSTEMS, LLC (US) 2009-09-29 — — US disclosed
US-20090118485-A1 OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES APPLIED BIOSYSTEMS INC. (US) 2009-05-07 — — US disclosed
US-7452672-B2 Methods of analyzing polynucleotides employing energy transfer dyes APPLIED BIOSYSTEMS INC. (US) 2008-11-18 — — US disclosed
US-7449149-B2 Kits useful for sequencing nucleic acids APPLIED BIOSYSTEMS INC. (US) 2008-11-11 — — US disclosed
US-7449298-B2 Methods of analyzing polynucleotides employing energy transfer dyes APPLIED BIOSYSTEMS INC. (US) 2008-11-11 — — US disclosed
US-20080268509-A1 METHODS OF LABELING POLYNUCLEOTIDES WITH ENERGY TRANSFER DYES APPLERA CORPORATION (US) 2008-10-30 — — US disclosed
US-7432058-B2 Methods of labeling nucleic acids with energy transfer dyes APPLERA CORPORATION (US) 2008-10-07 — — US disclosed
US-7423140-B2 Oligonucleotides and analogs labeled with energy transfer dyes APPLIED BIOSYSTEMS INC. (US) 2008-09-09 — — US disclosed
US-7388092-B2 Oligonucleotides and analogs labeled with energy transfer dyes APPLERA CORPORATION (US) 2008-06-17 — — US disclosed
US-20070207477-A1 KITS USEFUL FOR SEQUENCING NUCLEIC ACIDS APPLERA CORPORATION (US) 2007-09-06 — — US disclosed
US-20070161027-A1 OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES APPLERA CORPORATION (US) 2007-07-12 — — US disclosed
US-20070154925-A1 METHODS OF ANALYZING POLYNUCLEOTIDES EMPLOYING ENERGY TRANSFER DYES APPLERA CORPORATION (US) 2007-07-05 — — US disclosed
US-20070154924-A1 OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES APPLERA CORPORATION (US) 2007-07-05 — — US disclosed
US-20070154926-A1 Linkers for donor dyes to acceptor dyes for energy transfer between dyes with fluorescence APPLERA CORPORATION (US) 2007-07-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070154924-A1 OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES RBM28, TRDMT1, RPS28 CA9 4450/4885CA1 4070/4885CA2 3756/4885
US-20100280246-A1 ENERGY TRANSFER DYES WITH ENHANCED FLUORESCENCE SLC25A21, ZCCHC8, ZDHHC7 CA9 4073/4885CA1 3643/4885CA2 2865/4885
US-20070161027-A1 OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES RBM28, TRDMT1, RTCB CA9 4432/4885CA1 3990/4885CA2 3794/4885
US-20070154926-A1 Linkers for donor dyes to acceptor dyes for energy transfer between dyes with fluorescence SLC25A21, RPS28, ZCCHC8 CA9 4308/4885CA1 4145/4885CA2 3425/4885
US-20070207477-A1 KITS USEFUL FOR SEQUENCING NUCLEIC ACIDS RNGTT, POLRMT, MRM1 CA9 3414/4885CA1 3777/4885CA2 3277/4885
US-20090118485-A1 OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES RBM28, TRDMT1, RTCB CA9 4432/4885CA1 3990/4885CA2 3794/4885
US-20070154925-A1 METHODS OF ANALYZING POLYNUCLEOTIDES EMPLOYING ENERGY TRANSFER DYES POLRMT, NOP2, NSUN3 CA9 4759/4885CA1 4741/4885CA2 4342/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback