Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 7/20 | 0.45 |
| ▸ | CA1 | P00915 | 6/20 | 0.45 |
| ▸ | CA2 | P00918 | 6/20 | 0.45 |
| ▸ | SLC5A2 | P31639 | 5/20 | 0.45 |
| ▸ | CA12 | O43570 | 4/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13024595 | 0.96 | ESR1 (0.48) | ESR1P2RY6CA9CA1CA2 | |
| SCHEMBL13024605 | 0.96 | DNASE1L3 (0.45) | ESR1P2RY6CA9CA1CA2 | |
| SCHEMBL13041611 | 0.93 | MEN1 (0.47) | ESR1P2RY6CA9CA1CA2 | |
| SCHEMBL10293902 | 0.92 | ESR1 (0.47) | ESR1CA9CA1CA2SLC5A2 | |
| SCHEMBL13024599 | 0.92 | ESR1 (0.43) | ESR1P2RY6CA9CA1CA2 | |
| SCHEMBL10137968 | 0.91 | ESR1 (0.48) | ESR1P2RY6CA9CA1CA2 | |
| SCHEMBL13041614 | 0.91 | MEN1 (0.47) | ESR1P2RY6CA9CA1CA2 | |
| SCHEMBL14415030 | 0.91 | ESR1 (0.47) | ESR1CA9CA1CA2SLC5A2 | |
| SCHEMBL13711037 | 0.90 | ESR1 (0.47) | ESR1CA9CA1CA2SLC5A2 | |
| SCHEMBL13024593 | 0.89 | CA9 (0.47) | ESR1P2RY6CA9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100280246-A1 | ENERGY TRANSFER DYES WITH ENHANCED FLUORESCENCE | APPLERA CORPORATION (US) | 2010-11-04 | — | — | US | disclosed |
| US-7595162-B2 | Methods of labeling polynucleotides with energy transfer dyes | APPLIED BIOSYSTEMS, LLC (US) | 2009-09-29 | — | — | US | disclosed |
| US-20090118485-A1 | OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES | APPLIED BIOSYSTEMS INC. (US) | 2009-05-07 | — | — | US | disclosed |
| US-7452672-B2 | Methods of analyzing polynucleotides employing energy transfer dyes | APPLIED BIOSYSTEMS INC. (US) | 2008-11-18 | — | — | US | disclosed |
| US-7449298-B2 | Methods of analyzing polynucleotides employing energy transfer dyes | APPLIED BIOSYSTEMS INC. (US) | 2008-11-11 | — | — | US | disclosed |
| US-7449149-B2 | Kits useful for sequencing nucleic acids | APPLIED BIOSYSTEMS INC. (US) | 2008-11-11 | — | — | US | disclosed |
| US-20080268509-A1 | METHODS OF LABELING POLYNUCLEOTIDES WITH ENERGY TRANSFER DYES | APPLERA CORPORATION (US) | 2008-10-30 | — | — | US | disclosed |
| US-7432058-B2 | Methods of labeling nucleic acids with energy transfer dyes | APPLERA CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |
| US-7423140-B2 | Oligonucleotides and analogs labeled with energy transfer dyes | APPLIED BIOSYSTEMS INC. (US) | 2008-09-09 | — | — | US | disclosed |
| US-7399854-B2 | Regents labeled with energy transfer dyes | APPLERA CORPORATION (US) | 2008-07-15 | — | — | US | disclosed |
| US-7388092-B2 | Oligonucleotides and analogs labeled with energy transfer dyes | APPLERA CORPORATION (US) | 2008-06-17 | — | — | US | disclosed |
| US-20070207477-A1 | KITS USEFUL FOR SEQUENCING NUCLEIC ACIDS | APPLERA CORPORATION (US) | 2007-09-06 | — | — | US | disclosed |
| US-20070161026-A1 | REGENTS LABELED WITH ENERGY TRANSFER DYES | APPLERA CORPORATION (US) | 2007-07-12 | — | — | US | disclosed |
| US-20070161027-A1 | OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES | APPLERA CORPORATION (US) | 2007-07-12 | — | — | US | disclosed |
| US-20070154927-A1 | ENERGY TRANSFER DYES WITH ENHANCED FLUORESCENCE | APPLERA CORPORATION (US) | 2007-07-05 | — | — | US | disclosed |
| US-20070154924-A1 | OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES | APPLERA CORPORATION (US) | 2007-07-05 | — | — | US | disclosed |
| US-20070154925-A1 | METHODS OF ANALYZING POLYNUCLEOTIDES EMPLOYING ENERGY TRANSFER DYES | APPLERA CORPORATION (US) | 2007-07-05 | — | — | US | disclosed |
| US-20070154926-A1 | Linkers for donor dyes to acceptor dyes for energy transfer between dyes with fluorescence | APPLERA CORPORATION (US) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070154924-A1 | OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES | RBM28, TRDMT1, RPS28 | ESR1 1970/4885P2RY6 4215/4885CA9 4450/4885 |
| US-20100280246-A1 | ENERGY TRANSFER DYES WITH ENHANCED FLUORESCENCE | SLC25A21, ZCCHC8, ZDHHC7 | ESR1 2242/4885P2RY6 4446/4885CA9 4073/4885 |
| US-20070161027-A1 | OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES | RBM28, TRDMT1, RTCB | ESR1 1985/4885P2RY6 4273/4885CA9 4432/4885 |
| US-20070154926-A1 | Linkers for donor dyes to acceptor dyes for energy transfer between dyes with fluorescence | SLC25A21, RPS28, ZCCHC8 | ESR1 2304/4885P2RY6 4293/4885CA9 4308/4885 |
| US-20070161026-A1 | REGENTS LABELED WITH ENERGY TRANSFER DYES | SOAT1, GFPT1, CBR3 | ESR1 1296/4885P2RY6 4094/4885CA9 4519/4885 |
| US-20070207477-A1 | KITS USEFUL FOR SEQUENCING NUCLEIC ACIDS | RNGTT, POLRMT, MRM1 | ESR1 2411/4885P2RY6 4397/4885CA9 3414/4885 |
| US-20090118485-A1 | OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES | RBM28, TRDMT1, RTCB | ESR1 1985/4885P2RY6 4273/4885CA9 4432/4885 |
| US-20070154925-A1 | METHODS OF ANALYZING POLYNUCLEOTIDES EMPLOYING ENERGY TRANSFER DYES | POLRMT, NOP2, NSUN3 | ESR1 3757/4885P2RY6 3047/4885CA9 4759/4885 |
| US-20070154927-A1 | ENERGY TRANSFER DYES WITH ENHANCED FLUORESCENCE | SLC25A21, ZCCHC8, SLC25A1 | ESR1 2046/4885P2RY6 4355/4885CA9 3925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.