SCHEMBL13028028

SCHEMBL13028028

c1ccc(CC2(CCc3ccc(N(c4ccccc4)c4ccc(-c5ccc(N(c6ccccc6)c6ccc(CCC7(Cc8ccccc8)COC7)cc6)cc5)cc4)cc3)COC2)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP12 P39900 2/20 0.32
MMP13 P45452 2/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 2/20 0.31
MAPT P10636 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
POLB P06746 1/20 0.31
FAAH O00519 1/20 0.31
MGLL Q99685 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
OPRM1 P35372 3/20 0.30
FFAR1 O14842 1/20 0.30
CHRM2 P08172 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13028068 0.88 FAAH (0.34) MMP12MEN1KMT2AKDM4EALDH1A1
SCHEMBL13028026 0.80 OPRM1 (0.36) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL20652128 0.78 OPRM1 (0.38) MEN1KMT2AALDH1A1MAPTMGLL
SCHEMBL13028052 0.76 ALOX5 (0.36) CYP1A2SLC6A2SLC6A4SLC6A3
SCHEMBL13698980 0.75 MAOA (0.46) MMP12MMP13MEN1KMT2AKDM4E
SCHEMBL19012305 0.75 MAOA (0.46) MMP12MMP13MEN1KMT2AKDM4E
SCHEMBL21183917 0.74 FAAH (0.33) MEN1KMT2AFAAHMGLLKCNH2
SCHEMBL8018437 0.73 ALDH1A1 (0.38) ALDH1A1L3MBTL1OPRM1OPRL1KDM1A
SCHEMBL14727198 0.72 KCNH2 (0.48) MMP12MMP13MEN1KMT2AKDM4E
SCHEMBL18557204 0.72 NAAA (0.34) ALDH1A1L3MBTL1FAAHMGLLTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8525156-B2 Organic thin film transistor having an amorphous channel control layer with specified inozation potential IDEMITSU KOSAN CO., LTD. (JP) 2013-09-03 US disclosed
US-8525156-B2 Organic thin film transistor having an amorphous channel control layer with specified inozation potential IDEMITSU KOSAN CO., LTD. (JP) 2013-09-03 US disclosed
US-20100283041-A1 ORGANIC THIN FILM TRANSISTOR IDEMITSU KOSAN CO., LTD. (JP) 2010-11-11 US disclosed
US-20100283041-A1 ORGANIC THIN FILM TRANSISTOR IDEMITSU KOSAN CO., LTD. (JP) 2010-11-11 US disclosed
EP-2194582-A1 ORGANIC THIN FILM TRANSISTOR Idemitsu Kosan Co., Ltd. (JP) 2010-06-09 EP disclosed