Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 4/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
| ▸ | TK1 | P04183 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TK2 | O00142 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ADA | P00813 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13092956 | 1.00 | OGA (0.39) | OGASLC5A2TK1LMNAPIM1 | |
| SCHEMBL13265415 | 1.00 | OGA (0.39) | OGASLC5A2TK1LMNAPIM1 | |
| SCHEMBL8819151 | 1.00 | OGA (0.39) | OGASLC5A2TK1LMNAPIM1 | |
| SCHEMBL13102723 | 1.00 | OGA (0.39) | OGASLC5A2TK1LMNAPIM1 | |
| SCHEMBL24760374 | 1.00 | OGA (0.39) | OGASLC5A2TK1LMNAPIM1 | |
| SCHEMBL16556942 | 1.00 | OGA (0.39) | OGASLC5A2TK1LMNAPIM1 | |
| SCHEMBL24943578 | 1.00 | OGA (0.39) | OGASLC5A2TK1LMNAPIM1 | |
| SCHEMBL12526525 | 1.00 | OGA (0.39) | OGASLC5A2TK1LMNAPIM1 | |
| SCHEMBL22065208 | 1.00 | OGA (0.39) | OGASLC5A2TK1LMNAPIM1 | |
| SCHEMBL13852188 | 1.00 | OGA (0.39) | OGASLC5A2TK1LMNAPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427049-A | Inhibitors of malaria and plasmodium falciparum hexose transporters and uses thereof | 清华大学 | 2022-12-02 | — | — | CN | claimed |
| US-20140080768-A1 | PRODRUGS OF DHODH INHIBITORS AND THEIR USES | BROWN RUDNICK LLP | 2014-03-20 | — | — | US | claimed |
| CN-115427049-B | Inhibitors of malaria and plasmodium falciparum hexose transporters and uses thereof | 清华大学 | 2024-09-06 | — | — | CN | disclosed |
| CN-116615479-A | Polyester polyols comprising 2, 5-bis (hydroxymethyl) tetrahydrofuran | 巴斯夫欧洲公司 | 2023-08-18 | — | — | CN | disclosed |
| US-20230130134-A1 | METHOD OF TREATING VIRAL INFECTIONS WITH HEXOSE TYPE MONOSACCHARIDES AND ANALOGS THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-04-27 | — | — | US | disclosed |
| CN-115427049-A | Inhibitors of malaria and plasmodium falciparum hexose transporters and uses thereof | 清华大学 | 2022-12-02 | — | — | CN | disclosed |
| US-20210128467-A1 | MICRO-EMULSION CONTAINING CREATINE FATTY-ESTER, METHOD FOR PREPARING SAID MICRO-EMULSION AND USES THEREOF | Commissariat à l'énergie atomique et aux énergies alternatives (FR) | 2021-05-06 | — | — | US | disclosed |
| US-9850270-B2 | Non-caloric sweeteners and methods for synthesizing | CONAGEN INC. (US) | 2017-12-26 | — | — | US | disclosed |
| US-20170362268-A1 | STEVIOL GLYCOSIDE COMPOUNDS, COMPOSITIONS FOR ORAL INGESTION OR USE, AND METHOD FOR ENHANCING STEVIOL GLYCOSIDE SOLUBILITY | CARGILL, INCORPORATED (US) | 2017-12-21 | — | — | US | disclosed |
| EP-2982668-A2 | 2-(2-HYDROXYBIPHENYL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE DERIVATIVES AS FACTOR VIIA INHIBITORS FOR THE TREATMENT OF THROMBOEMBOLIC DISORDERS | Pharmacyclics LLC (US) | 2016-02-10 | — | — | EP | disclosed |
| US-9181280-B2 | Factor VIIa inhibitor | PHARMACYCLICS LLC (US) | 2015-11-10 | — | — | US | disclosed |
| US-20080275250-A1 | Factor Viia Inhibitor | PHARMACYCLICS, INC. (US) | 2008-11-06 | — | — | US | disclosed |
| US-7375129-B2 | Bis-indole pyrroles useful as antimicrobials agents | NEREUS PHARMACEUTICALS, INC. (US) | 2008-05-20 | — | — | US | disclosed |
| US-20070149601-A1 | Bis-indole pyrroles useful as antimicrobials agents | PRIVATE LIFE BIOMED AG (DE) | 2007-06-28 | — | — | US | disclosed |
| US-20070078082-A1 | Methods and compositions to treat glycosaminoglycan-associated molecular interactions | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2007-04-05 | — | — | US | disclosed |
| EP-1761504-A2 | FACTOR VIIA INHIBITOR | PHARMACYCLICS, INC. (US) | 2007-03-14 | — | — | EP | disclosed |
| US-20060205942-A1 | e.g. 2-{2-[545-carbamimidoyl-1H-benzoimidazol-2-yl)-6,2'-dihydroxy-5'-sulthmoyl-biphenyl-3-yl]-acetylsmino}-succinamic; anticoagulant, anticarcinogenic, antiinflammatory agent; deep vein thrombosis, rheumatoid arthritis, stroke | PHARMACYCLICS LLC | 2006-09-14 | — | — | US | disclosed |
| WO-2005118554-A2 | FACTOR VIIA INHIBITOR | PHARMACYCLICS, INC. (US) | 2005-12-15 | — | — | WO | disclosed |
| EP-1569912-A2 | 2-(2-HYDROXYBIPHENYL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE DERIVATIVES AS FACTOR VIIA INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004050637-A2 | 2-(2-HYDROXYBIPHENYL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE DERIVATIVES AS FACTOR VIIA INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2004-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140080768-A1 | PRODRUGS OF DHODH INHIBITORS AND THEIR USES | DHODH, DPYD, DHFR | OGA 362/4885SLC5A2 1063/4885TK1 535/4885 |
| US-20210128467-A1 | MICRO-EMULSION CONTAINING CREATINE FATTY-ESTER, METHOD FOR PREPARING SAID MICRO-EMULSION AND USES THEREOF | FABP7, MTTP, CETP | OGA 2865/4885SLC5A2 510/4885TK1 505/4885 |
| US-20170362268-A1 | STEVIOL GLYCOSIDE COMPOUNDS, COMPOSITIONS FOR ORAL INGESTION OR USE, AND METHOD FOR ENHANCING STEVIOL GLYCOSIDE SOLUBILITY | SI, SORD, TAS2R13 | OGA 880/4885SLC5A2 46/4885TK1 4414/4885 |
| US-20060205942-A1 | e.g. 2-{2-[545-carbamimidoyl-1H-benzoimidazol-2-yl)-6,2'-dihydroxy-5'-sulthmoyl-biphenyl-3-yl]-acetylsmino}-succinamic; anticoagulant, anticarcinogenic, antiinflammatory agent; deep vein thrombosis, rheumatoid arthritis, stroke | F7, F9, F5 | OGA 368/4885SLC5A2 3602/4885TK1 4807/4885 |
| US-20070149601-A1 | Bis-indole pyrroles useful as antimicrobials agents | IDO1, IDO2, TPH1 | OGA 4046/4885SLC5A2 4239/4885TK1 1084/4885 |
| US-20230130134-A1 | METHOD OF TREATING VIRAL INFECTIONS WITH HEXOSE TYPE MONOSACCHARIDES AND ANALOGS THEREOF | G6PD, FBP1, ALDOA | OGA 70/4885SLC5A2 25/4885TK1 173/4885 |
| US-20070078082-A1 | Methods and compositions to treat glycosaminoglycan-associated molecular interactions | HPSE, CD44, CSGALNACT1 | OGA 148/4885SLC5A2 1150/4885TK1 1831/4885 |
| US-20080275250-A1 | Factor Viia Inhibitor | F7, F9, F5 | OGA 1110/4885SLC5A2 4400/4885TK1 4540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.