Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408539 | 0.81 | ALDH1A1 (0.40) | IDO1TRPA1ALDH1A1TSHRTAAR1 | |
| SCHEMBL2822708 | 0.75 | NR1H2 (0.45) | RORCNR1H2NR1H3NR1I2TSHR | |
| SCHEMBL3819337 | 0.74 | KIF11 (0.45) | RORCNR1H2NR1H3NR1I2ALDH1A1 | |
| SCHEMBL15603600 | 0.74 | PDE2A (0.47) | NR1H2NR1H3IDO1TRPA1ALDH1A1 | |
| SCHEMBL16880438 | 0.74 | ALDH1A1 (0.37) | RORCNR1H2NR1H3NR1I2IDO1 | |
| SCHEMBL9694556 | 0.74 | RORC (0.39) | RORCTRPA1ALDH1A1TSHRMEN1 | |
| SCHEMBL8436560 | 0.73 | ESR1 (0.50) | NR1H2NR1H3IDO1TRPA1ALDH1A1 | |
| SCHEMBL16446207 | 0.73 | ALDH1A1 (0.40) | IDO1TRPA1ALDH1A1TSHRTAAR1 | |
| SCHEMBL16875453 | 0.73 | TRPA1 (0.40) | IDO1TRPA1ALDH1A1TSHRTAAR1 | |
| SCHEMBL10890440 | 0.73 | NR1H2 (0.54) | RORCNR1H2NR1H3NR1I2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184815-A1 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-ALPHA | MPM ASSET MANAGEMENT INVESTORS 2002 BVIII LLC | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184815-A1 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-ALPHA | PPARA, PPARD, PPARG | RORC 265/4885NR1H2 4/4885NR1H3 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.