Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3819337 | 0.80 | KIF11 (0.45) | NR1H2NR1H3TSHRRORCNR1I2 | |
| SCHEMBL10890440 | 0.79 | NR1H2 (0.54) | NR1H2NR1H3TSHRRORCCA2 | |
| SCHEMBL15177873 | 0.78 | TSHR (0.44) | NR1H2NR1H3TSHRMLYCDRORC | |
| SCHEMBL13046003 | 0.77 | MAPT (0.41) | NR1H2NR1H3RORCNR1I2TDP1 | |
| SCHEMBL19315792 | 0.76 | TSHR (0.46) | TSHRMLYCDCA2CA1CA5A | |
| SCHEMBL18073428 | 0.76 | TSHR (0.46) | TSHRMLYCDCA2CA1CA5A | |
| SCHEMBL8584704 | 0.75 | CA2 (0.48) | NR1H2NR1H3TSHRMLYCDRORC | |
| SCHEMBL15986322 | 0.75 | CA2 (0.40) | NR1H2NR1H3TSHRMLYCDRORC | |
| SCHEMBL2823641 | 0.75 | RORC (0.43) | NR1H2NR1H3TSHRRORCNR1I2 | |
| SCHEMBL18275111 | 0.74 | SRD5A2 (0.52) | NR1H2NR1H3TSHRMLYCDRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184815-A1 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-ALPHA | MPM ASSET MANAGEMENT INVESTORS 2002 BVIII LLC | 2010-07-22 | — | — | US | disclosed |
| WO-2010071813-A1 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-α | ARYX THERAPEUTICS, INC. (US) | 2010-06-24 | — | — | WO | disclosed |
| US-20070179263-A1 | Functional material comprising fluorine-containing compound | DAIKIN INDUSTRIES LTD. (JP) | 2007-08-02 | — | — | US | disclosed |
| US-20070179263-A1 | Functional material comprising fluorine-containing compound | DAIKIN INDUSTRIES LTD. (JP) | 2007-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070179263-A1 | Functional material comprising fluorine-containing compound | RER1, AFF1, FRG1 | NR1H2 1249/4885NR1H3 1519/4885TSHR 677/4885 |
| US-20100184815-A1 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-ALPHA | PPARA, PPARD, PPARG | NR1H2 4/4885NR1H3 5/4885TSHR 538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.