Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.50 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13046085 | 1.00 | P2RX3 (0.50) | P2RX3P2RX4P2RX2MEN1USP2 | |
| SCHEMBL30019683 | 0.94 | LMNA (0.48) | P2RX3P2RX4P2RX2MEN1USP2 | |
| SCHEMBL22983997 | 0.88 | P2RX3 (0.59) | P2RX3P2RX4P2RX2MEN1USP2 | |
| SCHEMBL4520396 | 0.87 | P2RX3 (0.58) | P2RX3P2RX4P2RX2MEN1USP2 | |
| SCHEMBL4520402 | 0.87 | P2RX3 (0.58) | P2RX3P2RX4P2RX2MEN1USP2 | |
| SCHEMBL8595775 | 0.87 | P2RX3 (0.58) | P2RX3P2RX4P2RX2MEN1USP2 | |
| SCHEMBL4148758 | 0.86 | P2RX3 (0.46) | P2RX3P2RX4P2RX2MEN1USP2 | |
| SCHEMBL17032324 | 0.86 | ADORA3 (0.46) | P2RX3P2RX4P2RX2PRMT6P2RY11 | |
| SCHEMBL17032318 | 0.86 | ADORA3 (0.46) | P2RX3P2RX4P2RX2PRMT6P2RY11 | |
| SCHEMBL5982554 | 0.85 | PRMT6 (0.62) | P2RX3P2RX4P2RX2MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100290990-A1 | METHOD FOR PREPARING A MARKED PURINE DERIVATIVE, SAID DERIVATIVE AND USES THEREOF | BARRE LOUISA | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100290990-A1 | METHOD FOR PREPARING A MARKED PURINE DERIVATIVE, SAID DERIVATIVE AND USES THEREOF | TPMT, NUDT1, DUT | P2RX3 135/4885P2RX4 131/4885P2RX2 132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.