SCHEMBL13046196

SCHEMBL13046196

c1ccc(-c2c3ccccc3c(-c3cccc(-c4cc5ccc(-c6ccccn6)nc5c5nc(-c6ccccn6)ccc45)c3)c3ccccc23)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.40
KDM4E B2RXH2 4/20 0.40
CCR1 P32246 3/20 0.40
CCR5 P51681 3/20 0.40
CCR8 P51685 3/20 0.40
HTT P42858 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
MAPK1 P28482 2/20 0.40
TP53 P04637 2/20 0.40
ALOX15 P16050 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
ALPL P05186 1/20 0.40
HSP90AA1 P07900 1/20 0.40
ALPI P09923 1/20 0.40
ALPG P10696 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
PIK3CD O00329 1/20 0.36
HSD17B10 Q99714 2/20 0.36
HPGD P15428 2/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13046243 0.94 LMNA (0.37) LMNAKDM4ECCR1CCR5CCR8
SCHEMBL24783508 0.92 KDM4E (0.39) LMNAKDM4ECCR1CCR5CCR8
SCHEMBL13046182 0.84 KDM4E (0.42) LMNAKDM4ECCR1CCR5CCR8
SCHEMBL21215787 0.82 LMNA (0.42) LMNAKDM4ECCR1CCR5CCR8
SCHEMBL26453925 0.82 PARP1 (0.40) LMNAKDM4ESMN1; SMN2HPGDMEN1
SCHEMBL13046226 0.81 KDM4E (0.40) LMNAKDM4ECCR1CCR5CCR8
SCHEMBL15198724 0.80 KDM4E (0.44) LMNAKDM4ECCR1CCR5CCR8
SCHEMBL24453781 0.80 MAPK1 (0.40) LMNAKDM4ECCR1CCR5CCR8
SCHEMBL14506026 0.79 KDM4E (0.56) LMNAKDM4ECCR1CCR5CCR8
SCHEMBL21215623 0.79 KDM4E (0.41) LMNAKDM4ECCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11552259-B1 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-01-10 US disclosed
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-29 US disclosed
US-10573823-B2 Organic electroluminescent device JOLED INC (JP) 2020-02-25 US disclosed
US-9978975-B2 Organic electroluminescence device JOLED INC (JP) 2018-05-22 US disclosed
US-9978975-B2 Organic electroluminescence device JOLED INC (JP) 2018-05-22 US disclosed
US-20160197289-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed
US-20160197289-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed
US-20150303380-A1 ORGANIC ELECTROLUMINESCENT DEVICE MAGNOLIA BLUE CORPORATION (JP) 2015-10-22 US disclosed
US-20150303380-A1 ORGANIC ELECTROLUMINESCENT DEVICE MAGNOLIA BLUE CORPORATION (JP) 2015-10-22 US disclosed
US-20150069351-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MAGNOLIA BLUE CORPORATION (JP) 2015-03-12 US disclosed
EP-2833429-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT Sony Corporation (JP) 2015-02-04 EP disclosed
EP-2833700-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Sony Corporation (JP) 2015-02-04 EP disclosed
US-7834346-B2 Nitrogenous heterocyclic derivative and organic electroluminescence device making use of the same IDEMITSU KOSAN CO., LTD. (JP) 2010-11-16 US disclosed
US-7834346-B2 Nitrogenous heterocyclic derivative and organic electroluminescence device making use of the same IDEMITSU KOSAN CO., LTD. (JP) 2010-11-16 US disclosed
US-20100108990-A1 NITROGENOUS HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-05-06 US disclosed
US-20100108990-A1 NITROGENOUS HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, TMEM109, SLC39A14 LMNA 1370/4885KDM4E 3416/4885CCR1 304/4885
US-20100108990-A1 NITROGENOUS HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME CYBA, NUDC, NUDT1 LMNA 936/4885KDM4E 636/4885CCR1 4859/4885
US-10573823-B2 Organic electroluminescent device L1CAM, NES, EML4 LMNA 831/4885KDM4E 2954/4885CCR1 2156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.