Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | GLP1R | P43220 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13995396 | 0.87 | PTGDR2 (0.39) | ALDH1A1MAPTPTGDR2 | |
| SCHEMBL807270 | 0.82 | LMNA (0.47) | LMNAGLAALDH1A1MAPTPTGS2 | |
| SCHEMBL23312355 | 0.80 | PTGS2 (0.39) | PTGS2PTGS1 | |
| SCHEMBL27709889 | 0.79 | LMNA (0.45) | LMNAGLAALDH1A1MAPTPTGS2 | |
| SCHEMBL13995391 | 0.76 | KIF11 (0.43) | PTGS2PTGS1 | |
| SCHEMBL16770543 | 0.74 | TP53 (0.59) | LMNA | |
| SCHEMBL17069212 | 0.74 | TP53 (0.59) | LMNA | |
| SCHEMBL2632875 | 0.74 | TP53 (0.59) | LMNA | |
| SCHEMBL13180776 | 0.73 | LMNA (0.39) | LMNAALDH1A1MAPT | |
| SCHEMBL7946495 | 0.73 | LMNA (0.49) | LMNAGLAALDH1A1MAPTPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7846980-B2 | Anion-conducting polymer, composition, and membrane | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2010-12-07 | — | — | US | disclosed |
| US-20090318575-A1 | ANION-CONDUCTING POLYMER, COMPOSITION, AND MEMBRANE | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2009-12-24 | — | — | US | disclosed |
| US-7582683-B2 | Polymer backbone with attached sulfonium, phosphazenium, phosphazene, and guanidinium residues; stability to aqueous alkali include a support embedded with sulfonium, phosphazenium, and guanidinium salts; 4, 4'-dihydroxybiphenyl derivative and 4,4'-dihalobiphenyl derivative comonomers; electrochemistry | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2009-09-01 | — | — | US | disclosed |
| US-20090023845-A1 | Anion-conducting polymer, composition, and membrane | PIVOVAR BRYAN S | 2009-01-22 | — | — | US | disclosed |
| US-20080312229-A1 | Organic Compounds | NOVARTIS AG | 2008-12-18 | — | — | US | disclosed |
| US-20080312229-A1 | Organic Compounds | NOVARTIS AG | 2008-12-18 | — | — | US | disclosed |
| WO-2007065683-A1 | ARYL ACETIC ACID AND ESTER DERIVATIVES AND THEIR USES AS ANTIINFLAMMATORY | NOVARTIS AG (CH) | 2007-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312229-A1 | Organic Compounds | DRD4, DRD1, SLC10A6 | LMNA 2494/4885GLA 2806/4885ALDH1A1 248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.