Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8595403 | 0.80 | PRKAB2 (0.43) | ALDH1A1HPGDKDM4EHSD17B10HTT | |
| SCHEMBL3761317 | 0.80 | PRKAB2 (0.43) | ALDH1A1HPGDKDM4EHSD17B10HTT | |
| SCHEMBL13060338 | 0.77 | TSHR (0.43) | ALDH1A1HPGDKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL14095931 | 0.77 | TSHR (0.43) | ALDH1A1HPGDKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL2427291 | 0.74 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4EHSD17B10HTT | |
| SCHEMBL2427488 | 0.74 | KDM4E (0.55) | ALDH1A1HPGDKDM4EHSD17B10HTT | |
| Hydrochloric Acid SCHEMBL6182013 | 0.73 | ALDH1A1 (0.43) | ALDH1A1HPGDKDM4EHSD17B10HTT | |
| SCHEMBL21496548 | 0.73 | MAPK1 (0.36) | ALDH1A1HPGDKDM4EHSD17B10HTT | |
| SCHEMBL3777567 | 0.72 | KDM4E (0.30) | ALDH1A1HPGDKDM4EHSD17B10HTT | |
| SCHEMBL6182009 | 0.72 | MAPK1 (0.35) | ALDH1A1HPGDKDM4EHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851220-B2 | Reduced level of background gene expression; responds to submicromolar concentrations of nonsteroidal ligand | INTREXON CORPORATION (US) | 2010-12-14 | — | — | US | disclosed |
| US-20080103113-A1 | Reduced level of background gene expression; responds to submicromolar concentrations of nonsteroidal ligand | HORMANN ROBERT E | 2008-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103113-A1 | Reduced level of background gene expression; responds to submicromolar concentrations of nonsteroidal ligand | NR5A1, NR0B2, NR0B1 | ALDH1A1 4095/4885HPGD 827/4885KDM4E 3645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.