Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HAAO | P46952 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRE | P78334 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL23142462 | 0.91 | PTGS2 (0.35) | MAPK1TDP1PTGS1PTGS2ALDH1A1 | |
| Dimethylformamide SCHEMBL25263371 | 0.90 | ALDH1A1 (0.32) | MAPK1ALDH1A1HPGDPOLBSMN1; SMN2 | |
| SCHEMBL27829365 | 0.85 | PARP1 (0.41) | TDP1MAPTALDH1A1KDM4E | |
| SCHEMBL6182009 | 0.81 | MAPK1 (0.35) | MAPK1CYP1A2TDP1MAPTTSHR | |
| SCHEMBL23142463 | 0.75 | — | — | |
| SCHEMBL13060339 | 0.73 | ALDH1A1 (0.36) | MAPK1TDP1MAPTTSHRALDH1A1 | |
| SCHEMBL3761317 | 0.71 | PRKAB2 (0.43) | MAPK1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL8595403 | 0.71 | PRKAB2 (0.43) | MAPK1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL2427291 | 0.70 | ALDH1A1 (0.44) | MAPK1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL2427488 | 0.70 | KDM4E (0.55) | PTGS1PTGS2ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4740948-A1 | PHARMACEUTICAL COMPOSITION COMPRISING 1,3-BENZODIOXOLE DERIVATIVE COMPOUND | Dong Wha Pharm. Co., Ltd. (KR) | 2026-05-13 | — | — | EP | disclosed |
| US-20250059180-A1 | 1,3-BENZODIOXOLE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | DONG WHA PHARM. CO., LTD. (KR) | 2025-02-20 | — | — | US | disclosed |
| WO-2025008783-A1 | PHARMACEUTICAL COMPOSITION COMPRISING 1,3-BENZODIOXOLE DERIVATIVE COMPOUND | 동화약품주식회사 | 2025-01-09 | — | — | WO | disclosed |
| EP-4464701-A1 | 1,3-BENZODIOXOLE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Dong Wha Pharm. Co., Ltd. (KR) | 2024-11-20 | — | — | EP | disclosed |
| US-11919912-B2 | Modulators of methyl modifying enzymes, compositions and uses thereof | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2024-03-05 | — | — | US | disclosed |
| WO-2023135564-A1 | 1,3-BENZODIOXOLE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 동화약품주식회사 | 2023-07-20 | — | — | WO | disclosed |
| EP-3797108-A1 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF | Constellation Pharmaceuticals, Inc. (US) | 2021-03-31 | — | — | EP | disclosed |
| EP-3781561-A1 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF | Constellation Pharmaceuticals, Inc. (US) | 2021-02-24 | — | — | EP | disclosed |
| CN-111989325-A | Modulators of methyl-modified enzymes, compositions and uses thereof | 星座制药公司 | 2020-11-24 | — | — | CN | disclosed |
| WO-2019204490-A1 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2019-10-24 | — | — | WO | disclosed |
| CN-106132954-B | 1,3- benzodioxole derivative | 第三共株式会社 | 2019-01-08 | — | — | CN | disclosed |
| CN-106132954-A | 1,3 benzodioxole derivant | 第三共株式会社 | 2016-11-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250059180-A1 | 1,3-BENZODIOXOLE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | CYP2C9, CYP1B1, SULT1A1 | MAPK1 1664/4885CYP1A2 29/4885TDP1 1681/4885 |
| US-11919912-B2 | Modulators of methyl modifying enzymes, compositions and uses thereof | TPMT, TET1, MAT1A | MAPK1 2606/4885CYP1A2 158/4885TDP1 280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.