Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HAAO | P46952 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | GABRE | P78334 | 1/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21496548 | 0.81 | MAPK1 (0.36) | MAPK1PTGS2CYP1A2PTGS1TSHR | |
| SCHEMBL9237663 | 0.80 | MAPK1 (0.33) | MAPK1CYP1A2 | |
| SCHEMBL9236403 | 0.76 | CYP2C9 (0.41) | TSHRMAPTMYCNR4A1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL23142462 | 0.74 | PTGS2 (0.35) | MAPK1PTGS2PTGS1ALDH1A1HPGD | |
| Dimethylformamide SCHEMBL25263371 | 0.73 | ALDH1A1 (0.32) | MAPK1SMN1; SMN2ALDH1A1HPGDPOLB | |
| SCHEMBL13060339 | 0.72 | ALDH1A1 (0.36) | MAPK1TSHRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8595403 | 0.70 | PRKAB2 (0.43) | MAPK1SMN1; SMN2ALDH1A1HPGDPOLB | |
| SCHEMBL3761317 | 0.70 | PRKAB2 (0.43) | MAPK1SMN1; SMN2ALDH1A1HPGDPOLB | |
| SCHEMBL2427291 | 0.69 | ALDH1A1 (0.44) | MAPK1SMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL2427488 | 0.69 | KDM4E (0.55) | PTGS2PTGS1SMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1160244-B1 | Isoxazole derivatives and their use as herbicides | BAYER AGRICULTURE LTD (GB) | 2005-10-19 | — | — | EP | disclosed |
| EP-1160244-A1 | Isoxazole derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LIMITED (GB) | 2001-12-05 | — | — | EP | disclosed |
| US-5489570-A | PRE- OR POST-EMERGENCE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1996-02-06 | — | — | US | disclosed |
| EP-0636622-A1 | Isoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-02-01 | — | — | EP | disclosed |